Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6088736 | 1.00 | HPGD (0.47) | HPGDALDH1A1HTTTSHRFGF23 | |
| SCHEMBL4073613 | 1.00 | HPGD (0.47) | HPGDALDH1A1HTTTSHRFGF23 | |
| SCHEMBL9841049 | 0.82 | ALOX12 (0.43) | HPGDALDH1A1HTTTSHRFGF23 | |
| SCHEMBL9841048 | 0.82 | ALOX12 (0.43) | HPGDALDH1A1HTTTSHRFGF23 | |
| SCHEMBL6779682 | 0.82 | FGF23 (0.57) | HPGDALDH1A1HTTTSHRFGF23 | |
| SCHEMBL29213057 | 0.80 | ALOX15 (0.45) | ALDH1A1TSHRLMNAL3MBTL1CYP3A4 | |
| SCHEMBL866769 | 0.80 | ALOX15 (0.45) | ALDH1A1TSHRLMNAL3MBTL1CYP3A4 | |
| SCHEMBL866768 | 0.80 | ALOX15 (0.45) | ALDH1A1TSHRLMNAL3MBTL1CYP3A4 | |
| SCHEMBL21515952 | 0.76 | CYP3A4 (0.41) | ALDH1A1HTTTSHRLMNAL3MBTL1 | |
| SCHEMBL18965889 | 0.76 | CYP3A4 (0.41) | ALDH1A1HTTTSHRLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115141199-B | Novel method for synthesizing rutaecarpine | 江西师范大学 | 2023-04-07 | — | — | CN | claimed |
| CN-115124530-B | Preparation method of evodiamine | 江西师范大学 | 2023-04-07 | — | — | CN | claimed |
| CN-115141199-A | Novel method for synthesizing rutaecarpine | 江西师范大学 | 2022-10-04 | — | — | CN | claimed |
| CN-115124530-A | Preparation method of evodiamine | 江西师范大学 | 2022-09-30 | — | — | CN | claimed |
| US-20070114155-A1 | Hydrotreating and/or hydrocracking catalyst of hydrocarbons and preparation thereof | TOTAL RAFFINAGE FRANCE (FR) | 2007-05-24 | — | — | US | claimed |
| JP-2007501701-A | — | — | 2007-02-01 | — | — | JP | claimed |
| EP-1660232-A1 | HYDROTREATING AND/OR HYDROCRACKING CATALYST OF HYDROCARBONS AND PREPARATION THEREOF | Total France (FR) | 2006-05-31 | — | — | EP | claimed |
| WO-2005016518-A1 | HYDROTREATING AND/OR HYDROCRACKING CATALYST OF HYDROCARBONS AND PREPARATION THEREOF | TOTAL FRANCE (FR) | 2005-02-24 | — | — | WO | claimed |
| CN-115141199-B | Novel method for synthesizing rutaecarpine | 江西师范大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-115141199-B | Novel method for synthesizing rutaecarpine | 江西师范大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-115124530-B | Preparation method of evodiamine | 江西师范大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-115124530-B | Preparation method of evodiamine | 江西师范大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-115141199-A | Novel method for synthesizing rutaecarpine | 江西师范大学 | 2022-10-04 | — | — | CN | disclosed |
| CN-115141199-A | Novel method for synthesizing rutaecarpine | 江西师范大学 | 2022-10-04 | — | — | CN | disclosed |
| US-20100056800-A1 | METHOD OF SYNTHESIZING 1H-INDAZOLE COMPOUNDS | THE OHIO STATE UNIVERSITY (US) | 2010-03-04 | — | — | US | disclosed |
| US-20100056800-A1 | METHOD OF SYNTHESIZING 1H-INDAZOLE COMPOUNDS | THE OHIO STATE UNIVERSITY (US) | 2010-03-04 | — | — | US | disclosed |
| EP-1660232-B1 | HYDROTREATING AND/OR HYDROCRACKING CATALYST OF HYDROCARBONS AND PREPARATION THEREOF | TOTAL RAFFINAGE MARKETING (FR) | 2009-07-22 | — | — | EP | disclosed |
| US-20070114155-A1 | Hydrotreating and/or hydrocracking catalyst of hydrocarbons and preparation thereof | TOTAL RAFFINAGE FRANCE (FR) | 2007-05-24 | — | — | US | disclosed |
| EP-1660232-A1 | HYDROTREATING AND/OR HYDROCRACKING CATALYST OF HYDROCARBONS AND PREPARATION THEREOF | Total France (FR) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005016518-A1 | HYDROTREATING AND/OR HYDROCRACKING CATALYST OF HYDROCARBONS AND PREPARATION THEREOF | TOTAL FRANCE (FR) | 2005-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056800-A1 | METHOD OF SYNTHESIZING 1H-INDAZOLE COMPOUNDS | CYP2E1, CYP1B1, CYP1A1 | HPGD 204/4885ALDH1A1 418/4885HTT 2751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.