SCHEMBL1896783

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12668507	0.84	ALDH1A1 (0.50)	ALDH1A1NPSR1TMEM97SIGMAR1LMNA
	SCHEMBL1897052	0.82	ALDH1A1 (0.46)	ALDH1A1NPSR1TMEM97SIGMAR1LMNA
	SCHEMBL1899028	0.82	ALDH1A1 (0.46)	ALDH1A1NPSR1TMEM97SIGMAR1LMNA
	SCHEMBL3747832	0.75	GAA (0.51)	GAAALDH1A1TDP1KMT2APOLB
	SCHEMBL9395019	0.74	GAA (0.66)	GAAALDH1A1TDP1SMN1; SMN2RAB9A
	SCHEMBL17577828	0.72	GAA (0.50)	GAAALDH1A1TDP1BRD4KMT2A
	SCHEMBL12702854	0.71	GAA (0.67)	GAAALDH1A1TDP1
	SCHEMBL1895133	0.71	CNR1 (0.41)	TMEM97SIGMAR1HSD17B10KMT2ANPC1
	SCHEMBL1589919	0.71	GAA (0.58)	GAAALDH1A1TDP1LMNASMN1; SMN2
	SCHEMBL1589992	0.70	GAA (0.48)	GAAALDH1A1TDP1SMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.