Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 3/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10934190 | 0.90 | ALDH1A3 (0.48) | PTPN5ALDH1A3NR1H4KMT2ACYP3A4 | |
| SCHEMBL143873 | 0.85 | ALDH1A3 (0.52) | ALDH1A3KMT2ACYP2D6PARP10BCL2 | |
| SCHEMBL10000943 | 0.84 | MAPT (0.48) | PTPN5KMT2ACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13283362 | 0.84 | NR1H4 (0.53) | PTPN5ALDH1A3NR1H4KMT2ACYP3A4 | |
| SCHEMBL19778458 | 0.84 | MMP14 (0.43) | PTPN5NR1H4POLBACACBACACA | |
| SCHEMBL16260241 | 0.84 | MMP14 (0.43) | PTPN5NR1H4POLBACACBACACA | |
| SCHEMBL17306110 | 0.84 | KMT2A (0.46) | NR1H4KMT2ACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL16191360 | 0.83 | CYP2C9 (0.50) | PTPN5CYP3A4CYP2D6CYP2C9HIF1A | |
| SCHEMBL13712346 | 0.82 | RAB9A (0.50) | KMT2ACYP3A4CYP2D6CYP2C9HIF1A | |
| SCHEMBL12552792 | 0.82 | ALDH1A1 (0.46) | PTPN5ALDH1A3NR1H4KMT2APARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017100602-A1 | AMINIMIDE COMPOSITIONS | PPG INDUSTRIES OHIO, INC. (US) | 2017-06-15 | — | — | WO | disclosed |