Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10962854 | 0.85 | VNN1 (0.56) | VNN1L3MBTL1TDP1ATMCES2 | |
| SCHEMBL7527957 | 0.81 | CES2 (0.48) | L3MBTL1TDP1MTNR1AMTNR1BCES2 | |
| SCHEMBL28295321 | 0.81 | L3MBTL1 (0.54) | VNN1L3MBTL1TDP1ATMCES2 | |
| SCHEMBL23784226 | 0.79 | TDP1 (0.51) | VNN1L3MBTL1TDP1ATMCES2 | |
| SCHEMBL8619264 | 0.78 | CES1 (0.64) | L3MBTL1TDP1CES2CES1AKR1B1 | |
| SCHEMBL8620925 | 0.77 | ALDH1A1 (0.61) | VNN1L3MBTL1TDP1CES2CES1 | |
| SCHEMBL7858 | 0.77 | KDM4E (0.69) | MTNR1AMTNR1BHPGDMEN1KMT2A | |
| SCHEMBL15561464 | 0.76 | NPC1 (0.64) | VNN1GAAHPGDMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL31736052 | 0.76 | KDM4E (0.67) | L3MBTL1HPGDMEN1KMT2AALDH1A1 | |
| Acetone SCHEMBL7728200 | 0.76 | L3MBTL1 (0.56) | VNN1L3MBTL1TDP1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017097838-A1 | METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF SYSTEMIC SCLEROSIS | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2017-06-15 | — | — | WO | disclosed |