Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14906667 | 0.89 | KDM4E (0.46) | KDM4ENPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL18973764 | 0.80 | ACHE (0.55) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14906664 | 0.80 | KMT2A (0.42) | KDM4ENPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL21017252 | 0.80 | KDM4E (0.54) | KDM4ENPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL14892370 | 0.76 | NPC1 (0.49) | KDM4ENPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL12289543 | 0.74 | CBFB (0.50) | KDM4ENPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL30343725 | 0.74 | NPBWR1 (0.50) | KDM4ENPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL19994514 | 0.74 | NPBWR1 (0.50) | KDM4ENPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL14892594 | 0.74 | ALDH1A1 (0.43) | KDM4ENPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL20001628 | 0.73 | KDM4E (0.47) | KDM4ENPC1RAB9ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2556058-B1 | RADIOPROTECTOR COMPOUNDS AND METHODS | PETER MACCALLUM CANCER INST (AU) | 2017-06-14 | — | — | EP | disclosed |