SCHEMBL1897418

SCHEMBL1897418

CCCCc1ccc(-c2cc[c]cc2-c2ccccc2)c(CCCC)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMB5 P28074 1/20 0.44
GPR3 P46089 1/20 0.39
HSD11B1 P28845 2/20 0.38
SKP2 Q13309 1/20 0.36
HTT P42858 2/20 0.34
APAF1 O14727 1/20 0.34
MAPT P10636 1/20 0.34
THRB P10828 1/20 0.34
MAPK1 P28482 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
RARB P10826 3/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPK8 P45983 1/20 0.33
BRS3 P32247 1/20 0.33
TLR8 Q9NR97 1/20 0.33
AGTR1 P30556 1/20 0.32
AGTR2 P50052 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27836085 0.85 PSMB5 (0.51) PSMB5GPR3HSD11B1SKP2HTT
SCHEMBL27836086 0.81 PSMB5 (0.52) PSMB5GPR3HSD11B1SKP2HTT
SCHEMBL9024571 0.80 GPR3 (0.55) PSMB5GPR3HSD11B1SKP2HTT
SCHEMBL1374849 0.79 PSMB5 (0.38) PSMB5HSD11B1TLR8
SCHEMBL1370515 0.79 PSMB5 (0.38) PSMB5HSD11B1TLR8
SCHEMBL1900101 0.79 PDCD1 (0.34) PSMB5HSD11B1
SCHEMBL1897415 0.77 PSMB5 (0.44) PSMB5GPR3HSD11B1SKP2HTT
SCHEMBL1840982 0.76 HSD11B1 (0.38) PSMB5HSD11B1L3MBTL1RARBSMN1; SMN2
SCHEMBL1995984 0.75 PSMB5 (0.45) PSMB5GPR3HSD11B1HTTAPAF1
SCHEMBL11325207 0.74 PSMB5 (0.61) PSMB5GPR3HSD11B1SKP2RARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2319887-A1 METHOD FOR MANUFACTURING MOLDED ARTICLE Teijin Chemicals, Ltd. (JP) 2011-05-11 EP disclosed