Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 5/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18975269 | 0.94 | BACE1 (0.45) | BACE1PRMT5WDR77ABCB1MEN1 | |
| SCHEMBL19489857 | 0.92 | BACE1 (0.43) | BACE1PRMT5WDR77ABCB1MEN1 | |
| SCHEMBL19489854 | 0.89 | BACE1 (0.41) | BACE1PRMT5WDR77ABCB1ALDH1A1 | |
| SCHEMBL18975189 | 0.88 | ALDH1A1 (0.44) | BACE1PRMT5WDR77MEN1KMT2A | |
| SCHEMBL18970111 | 0.85 | TDP1 (0.39) | BACE1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5557205 | 0.84 | ALDH1A1 (0.46) | BACE1PRMT5WDR77MEN1KMT2A | |
| SCHEMBL22446648 | 0.82 | BACE1 (0.39) | BACE1PRMT5WDR77ABCB1ALDH1A1 | |
| SCHEMBL18970104 | 0.82 | HSD17B10 (0.38) | MEN1KMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL18970241 | 0.79 | SLC6A9 (0.36) | MEN1KMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL22730606 | 0.79 | TDP1 (0.34) | MEN1KMT2AKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11021451-B2 | Contrast agents | BRACCO IMAGING S.P.A. (IT) | 2021-06-01 | — | — | US | disclosed |
| EP-3386953-B1 | CONTRAST AGENTS | BRACCO IMAGING SPA (IT) | 2020-10-21 | — | — | EP | disclosed |
| US-20200325108-A1 | CONTRAST AGENTS | BRACCO IMAGING S.P.A. (IT) | 2020-10-15 | — | — | US | disclosed |
| US-10781188-B2 | Contrast agents | BRACCO IMAGING S.P.A. (IT) | 2020-09-22 | — | — | US | disclosed |
| WO-2017098038-A1 | CONTRAST AGENTS | BRACCO IMAGING SPA (IT) | 2017-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11021451-B2 | Contrast agents | SLC39A14, ABCB7, SLC40A1 | BACE1 4866/4885PRMT5 3077/4885WDR77 3670/4885 |
| US-20200325108-A1 | CONTRAST AGENTS | SLC39A14, ABCB7, SLC40A1 | BACE1 4866/4885PRMT5 3077/4885WDR77 3670/4885 |
| US-10781188-B2 | Contrast agents | SLC39A14, ABCB7, SLC40A1 | BACE1 4866/4885PRMT5 3077/4885WDR77 3670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.