Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18976230 | 0.92 | PRKDC (0.52) | PRKDCCD274TP53THRBKMT2A | |
| SCHEMBL18975731 | 0.90 | AR (0.52) | PRKDCTP53ARHRH3THRB | |
| SCHEMBL18976141 | 0.89 | AR (0.51) | TP53ARHRH3THRB | |
| SCHEMBL18976489 | 0.87 | AR (0.41) | PRKDCCD274ARTHRB | |
| SCHEMBL18976206 | 0.84 | RAB9A (0.46) | PRKDCCD274TP53THRBKMT2A | |
| SCHEMBL20581159 | 0.84 | TP53 (0.50) | TP53ARHRH3THRBKMT2A | |
| SCHEMBL18976117 | 0.84 | GAA (0.45) | PRKDCCD274THRBKMT2A | |
| SCHEMBL21940850 | 0.82 | AR (0.45) | PRKDCCD274TP53ARTHRB | |
| SCHEMBL21941150 | 0.81 | AR (0.44) | PRKDCCD274TP53ARTHRB | |
| SCHEMBL5001090 | 0.80 | TOP1 (0.40) | PRKDCCD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10640507-B2 | PBD antibacterial agents | KING'S COLLEGE LONDON (GB) | 2020-05-05 | — | — | US | disclosed |
| WO-2017098257-A1 | PBD ANTIBACTERIAL AGENTS | KING'S COLLEGE LONDON (GB) | 2017-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10640507-B2 | PBD antibacterial agents | OPRD1, XDH, SBDS | PRKDC 4382/4885CD274 659/4885TP53 4614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.