Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 8/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18976150 | 0.83 | AR (0.58) | KMT2AHTTHPGDARLMNA | |
| SCHEMBL4486085 | 0.82 | AR (0.42) | KMT2AHTTMEN1HPGDNPSR1 | |
| SCHEMBL12438322 | 0.81 | MAPK1 (0.44) | KMT2AHTTMEN1L3MBTL1AR | |
| SCHEMBL1662655 | 0.81 | AR (0.51) | KMT2AMEN1L3MBTL1ARALDH1A1 | |
| SCHEMBL2114774 | 0.79 | AR (0.51) | KMT2AMEN1L3MBTL1ARLMNA | |
| Hydrochloric Acid SCHEMBL6151019 | 0.79 | AR (0.50) | KMT2AMEN1L3MBTL1ARALDH1A1 | |
| SCHEMBL2399432 | 0.79 | ALDH1A1 (0.43) | KMT2AHTTMEN1L3MBTL1AR | |
| SCHEMBL5750827 | 0.79 | AR (0.40) | KMT2AHTTMEN1HPGDNPSR1 | |
| SCHEMBL27520536 | 0.78 | AR (0.39) | KMT2AHTTMEN1L3MBTL1AR | |
| SCHEMBL2388875 | 0.77 | MEN1 (0.44) | KMT2AHTTMEN1ARALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10640507-B2 | PBD antibacterial agents | KING'S COLLEGE LONDON (GB) | 2020-05-05 | — | — | US | disclosed |
| US-10640507-B2 | PBD antibacterial agents | KING'S COLLEGE LONDON (GB) | 2020-05-05 | — | — | US | disclosed |
| US-20180354958-A1 | PBD ANTIBACTERIAL AGENTS | Secretary of State for Health and Social Care (GB) | 2018-12-13 | — | — | US | disclosed |
| WO-2017098257-A1 | PBD ANTIBACTERIAL AGENTS | KING'S COLLEGE LONDON (GB) | 2017-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10640507-B2 | PBD antibacterial agents | OPRD1, XDH, SBDS | KMT2A 3038/4885HTT 4805/4885MEN1 3217/4885 |
| US-20180354958-A1 | PBD ANTIBACTERIAL AGENTS | OPRD1, XDH, SBDS | KMT2A 3038/4885HTT 4805/4885MEN1 3217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.