Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18976321 | 0.80 | ALDH1A1 (0.46) | MAPTPOLBALDH1A1HPGDL3MBTL1 | |
| SCHEMBL22588038 | 0.75 | PIM1 (0.50) | MAPTALDH1A1HPGDL3MBTL1RAB9A | |
| SCHEMBL18976336 | 0.69 | ALDH1A1 (0.56) | HRH4MAPTPOLBALDH1A1HPGD | |
| SCHEMBL20581440 | 0.69 | HRH4 (0.44) | HRH4MAPTPOLBALDH1A1HPGD | |
| SCHEMBL18889240 | 0.69 | RAB9A (0.60) | HRH4MAPTPOLBALDH1A1HPGD | |
| SCHEMBL18976128 | 0.68 | MAPT (0.47) | MAPTPOLBALDH1A1HPGDRAB9A | |
| SCHEMBL20581201 | 0.68 | HRH4 (0.41) | HRH4MAPTPOLBALDH1A1HPGD | |
| SCHEMBL7086091 | 0.68 | POLB (0.63) | HRH4MAPTPOLBALDH1A1HPGD | |
| SCHEMBL19864572 | 0.64 | ALDH1A1 (1.00) | HRH4MAPTPOLBALDH1A1HPGD | |
| SCHEMBL15170873 | 0.64 | ALDH1A1 (1.00) | HRH4MAPTPOLBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017098257-A1 | PBD ANTIBACTERIAL AGENTS | KING'S COLLEGE LONDON (GB) | 2017-06-15 | — | — | WO | disclosed |