Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.41 |
| ▸ | IGF1R | P08069 | 3/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD1 | P21728 | 3/20 | 0.38 |
| ▸ | DRD4 | P21917 | 3/20 | 0.38 |
| ▸ | DRD5 | P21918 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11541519 | 0.77 | ALOX15 (0.67) | BACE1ALOX15IGF1RMAPTKDM4E | |
| SCHEMBL29362192 | 0.70 | FOLH1 (0.33) | BACE1ALOX15IGF1R | |
| SCHEMBL64008 | 0.70 | FOLH1 (0.33) | BACE1ALOX15IGF1R | |
| SCHEMBL16982325 | 0.69 | GABRA1 (0.45) | BACE1ALOX15IGF1RAKR1B1MAPT | |
| SCHEMBL18328794 | 0.66 | ALDH1A1 (0.51) | ALOX15MAPTKDM4EALDH1A1GAA | |
| SCHEMBL28880594 | 0.65 | ALOX15 (0.75) | BACE1ALOX15IGF1RMAPTKDM4E | |
| SCHEMBL1021086 | 0.65 | ALOX5 (0.71) | BACE1ALOX15IGF1RAKR1B1MAPT | |
| SCHEMBL10450798 | 0.65 | KDM4E (0.65) | BACE1ALOX15IGF1RAKR1B1MAPT | |
| SCHEMBL22499941 | 0.65 | BACE1 (0.75) | BACE1ALOX15MAPTKDM4EALDH1A1 | |
| SCHEMBL19303094 | 0.65 | ALOX15 (0.50) | BACE1ALOX15IGF1RMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2810564-B1 | Sensation masking composition | TAKASAGO INT CORP (USA) (US) | 2017-06-14 | — | — | EP | disclosed |