Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2557643 | 0.82 | PKM (0.58) | PKMPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL16372253 | 0.81 | NAMPT (0.39) | CYP2C9PKMPOLBALDH1A1USP2 | |
| SCHEMBL15765139 | 0.81 | MMP2 (0.49) | ALDH1A1USP2TSHRLMNA | |
| SCHEMBL21510169 | 0.81 | PKM (0.59) | PKMPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL19746052 | 0.80 | AKR1C3 (0.51) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL7606500 | 0.80 | POLB (0.56) | CYP2C9PKMPOLBALDH1A1CYP2D6 | |
| SCHEMBL31426435 | 0.79 | MBTD1 (0.52) | ALDH1A1CYP3A4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13188195 | 0.79 | NAMPT (0.55) | POLBALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL17841225 | 0.79 | PKM (0.58) | PKMPOLBALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL20791554 | 0.79 | MAPT (0.67) | ALDH1A1MEN1KMT2ASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019493-B1 | MODIFIED BET-PROTEIN INHIBITING DIHYDROCHINOXALINONES AND DIHYDROPYRIDOPYRAZINONES | Bayer Pharma AG (DE) | 2017-06-14 | — | — | EP | disclosed |