SCHEMBL1897798

SCHEMBL1897798

C=CC(=O)Oc1ccc(CCC(=O)O)cc1

nearest known ligand 0.68

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.68
FFAR1 O14842 13/20 0.57
FFAR4 Q5NUL3 3/20 0.53
LMNA P02545 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
SRD5A2 P31213 1/20 0.50
KEAP1 Q14145 1/20 0.50
F2 P00734 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17791334 0.87 THRB (0.79) THRBFFAR1
SCHEMBL12404426 0.85 THRB (0.51) THRBFFAR1FFAR4LMNAL3MBTL1
SCHEMBL9906556 0.85 THRB (0.71) THRBFFAR1LMNAL3MBTL1
SCHEMBL242424 0.84 THRB (0.78) THRBFFAR1
SCHEMBL14117088 0.83 FFAR1 (0.54) THRBFFAR1FFAR4LMNAL3MBTL1
SCHEMBL24517163 0.82 THRB (0.81) THRBFFAR1
SCHEMBL22566602 0.82 THRB (0.72) THRBFFAR1
SCHEMBL22566502 0.82 THRB (0.72) THRBFFAR1
SCHEMBL342562 0.82 THRB (0.72) THRB
SCHEMBL7869603 0.82 THRB (0.62) THRBFFAR1LMNASRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170174992-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, COMPOSITION, LIQUID CRYSTAL POLYMERIZATION FILM-KIND THEREOF AND USE THEREOF JNC CORPORATION (JP) 2017-06-22 US disclosed
EP-1813594-B1 POLYMERIZABLE COMPOUND AND COMPOSITION CONTAINING THE POLYMERIZABLE COMPOUND ADEKA CORP (JP) 2011-05-11 EP disclosed
CN-101052613-B Polymerizable compound and composition containing same ADEKA CORP 2011-04-13 CN disclosed
US-7683203-B2 Polymerizable compound and composition containing the polymerizable compound ADEKA CORPORATION (JP) 2010-03-23 US disclosed
US-7683203-B2 Polymerizable compound and composition containing the polymerizable compound ADEKA CORPORATION (JP) 2010-03-23 US disclosed
US-20070282087-A1 Polymerizable Compound And Composition Containing The Polymerizable Compound ADEKA CORPORATION (JP) 2007-12-06 US disclosed
US-20070282087-A1 Polymerizable Compound And Composition Containing The Polymerizable Compound ADEKA CORPORATION (JP) 2007-12-06 US disclosed
US-20070282087-A1 Polymerizable Compound And Composition Containing The Polymerizable Compound ADEKA CORPORATION (JP) 2007-12-06 US disclosed
CN-101052613-A Polymerizable compound and composition containing same ADEKA CORP (JP) 2007-10-10 CN disclosed
EP-1813594-A1 POLYMERIZABLE COMPOUND AND COMPOSITION CONTAINING THE POLYMERIZABLE COMPOUND Adeka Corporation (JP) 2007-08-01 EP disclosed
EP-1813594-A1 POLYMERIZABLE COMPOUND AND COMPOSITION CONTAINING THE POLYMERIZABLE COMPOUND Adeka Corporation (JP) 2007-08-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170174992-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, COMPOSITION, LIQUID CRYSTAL POLYMERIZATION FILM-KIND THEREOF AND USE THEREOF RCC1, CHRM1, PFN1 THRB 4867/4885FFAR1 1740/4885FFAR4 2896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.