Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17791334 | 0.86 | THRB (0.79) | THRBTP53ALDH1A1F2RL1NFKB1 | |
| SCHEMBL1897798 | 0.85 | THRB (0.68) | THRBLMNAL3MBTL1FFAR1 | |
| SCHEMBL14565371 | 0.83 | THRB (0.65) | THRBLMNAKDM4ENPC1TP53 | |
| SCHEMBL4596017 | 0.83 | THRB (1.00) | THRBLMNANPC1MAPTRAB9A | |
| SCHEMBL242424 | 0.82 | THRB (0.78) | THRBKMT2AMEN1FFAR1 | |
| SCHEMBL404104 | 0.82 | ALDH1A1 (0.57) | THRBLMNAKDM4ENPC1TP53 | |
| SCHEMBL19292333 | 0.81 | NPC1 (0.49) | THRBLMNAKDM4ENPC1TP53 | |
| SCHEMBL25558472 | 0.81 | THRB (0.73) | THRBLMNAMAPTALDH1A1KMT2A | |
| SCHEMBL7787037 | 0.81 | THRB (0.97) | THRBLMNANPC1MAPTRAB9A | |
| SCHEMBL24517163 | 0.81 | THRB (0.81) | THRBCYP3A4ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8197710-B2 | Polymerizable compound and polymerizable composition | ADEKA CORPORATION (JP) | 2012-06-12 | — | — | US | disclosed |
| US-8066906-B2 | Polymerizable compound and polymerizable composition | ADEKA CORPORATION (JP) | 2011-11-29 | — | — | US | disclosed |
| US-7981320-B2 | Polymerizable composition | ADEKA CORPORATION (JP) | 2011-07-19 | — | — | US | disclosed |
| US-7931825-B2 | Polymerizable composition | ADEKA CORPORATION (JP) | 2011-04-26 | — | — | US | disclosed |
| US-7919009-B2 | Polymerizable compounds and polymerizable compositions | ADEKA CORPORATION (JP) | 2011-04-05 | — | — | US | disclosed |
| US-7910021-B2 | Polymerizable optical active compound and polymerizable composition containing the same | ADEKA CORPORATION (JP) | 2011-03-22 | — | — | US | disclosed |
| US-20100320419-A1 | POLYMERIZABLE COMPOUND AND POLYMERIZABLE COMPOSITION | ADEKA CORPORATION (JP) | 2010-12-23 | — | — | US | disclosed |
| US-20100294990-A1 | POLYMERIZABLE COMPOUND AND POLYMERIZABLE COMPOSITION | ADEKA CORPORATION (JP) | 2010-11-25 | — | — | US | disclosed |
| US-20100090163-A1 | POLYMERIZABLE COMPOSITION | ADEKA CORPORATION (JP) | 2010-04-15 | — | — | US | disclosed |
| US-20100032621-A1 | POLYMERIZABLE COMPOUNDS AND POLYMERIZABLE COMPOSITIONS | ADEKA CORPORATION (JP) | 2010-02-11 | — | — | US | disclosed |
| US-20100032620-A1 | POLYMERIZABLE OPTICAL ACTIVE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE SAME | ADEKA CORPORATION (JP) | 2010-02-11 | — | — | US | disclosed |
| US-20090294730-A1 | POLYMERIZABLE COMPOSITION | ADEKA CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100320419-A1 | POLYMERIZABLE COMPOUND AND POLYMERIZABLE COMPOSITION | NOS1, NOS2, PYM1 | THRB 1994/4885LMNA 2363/4885KDM4E 3075/4885 |
| US-20100032620-A1 | POLYMERIZABLE OPTICAL ACTIVE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE SAME | C1S, PYM1, MCCC2 | THRB 3247/4885LMNA 399/4885KDM4E 2413/4885 |
| US-20100294990-A1 | POLYMERIZABLE COMPOUND AND POLYMERIZABLE COMPOSITION | PYM1, SCO2, ZYX | THRB 1211/4885LMNA 1333/4885KDM4E 2811/4885 |
| US-20100032621-A1 | POLYMERIZABLE COMPOUNDS AND POLYMERIZABLE COMPOSITIONS | CHRM1, CHRM2, CCNE1 | THRB 4880/4885LMNA 73/4885KDM4E 669/4885 |
| US-20090294730-A1 | POLYMERIZABLE COMPOSITION | SCO2, NAT1, CORO1C | THRB 985/4885LMNA 1809/4885KDM4E 3930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.