Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE1A | P54750 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3298438 | 0.85 | PDCD1 (0.47) | CYP2D6MEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL5073898 | 0.82 | TTR (0.44) | CYP2D6CYP1A2GABRA1GABRG2GABRB3 | |
| SCHEMBL506623 | 0.82 | CYP2D6 (0.45) | CYP2D6MEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30569427 | 0.82 | CYP2D6 (0.45) | CYP2D6MEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL18381130 | 0.79 | ADRA2A (0.39) | CYP3A4GABRA1GABRG2GABRB3EPAS1 | |
| SCHEMBL18621584 | 0.79 | KMT2A (0.41) | KMT2AEPAS1 | |
| SCHEMBL30125012 | 0.79 | DUSP5 (0.38) | CYP2D6CA12APEX1HDAC3HDAC1 | |
| SCHEMBL28589728 | 0.79 | DUSP5 (0.38) | CYP2D6CA12APEX1HDAC3HDAC1 | |
| SCHEMBL6466209 | 0.77 | ALOX15 (0.46) | CA12BCAT2 | |
| SCHEMBL10777232 | 0.77 | CYP2D6 (0.49) | CYP2D6KMT2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3181563-A1 | CONDENSED 11-MEMBER RING COMPOUND AND AGRICULTURE AND HORTICULTURAL FUNGICIDE COMPRISING SAME | SDS Biotech K. K. (JP) | 2017-06-21 | — | — | EP | claimed |
| EP-3181563-B1 | CONDENSED 11-MEMBER RING COMPOUND AND AGRICULTURE AND HORTICULTURAL FUNGICIDE COMPRISING SAME | SDS BIOTECH CORP (JP) | 2019-02-06 | — | — | EP | disclosed |
| US-10104891-B2 | Fused 11-membered compounds and agricultural/horticultural fungicides containing them | SDS BIOTECH K.K. (JP) | 2018-10-23 | — | — | US | disclosed |
| US-20180235225-A1 | FUSED 11-MEMBERED COMPOUNDS AND AGRICULTURAL/HORTICULTURAL FUNGICIDES CONTAINING THEM | BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT | 2018-08-23 | — | — | US | disclosed |
| US-9980487-B2 | Fused 11-membered compounds and agricultural/horticultural fungicides containing them | SDS BIOTECH K.K. (JP) | 2018-05-29 | — | — | US | disclosed |
| US-20170231226-A1 | FUSED 11-MEMBERED COMPOUNDS AND AGRICULTURAL/HORTICULTURAL FUNGICIDES CONTAINING THEM | SDS BIOTECH K.K. (JP) | 2017-08-17 | — | — | US | disclosed |
| EP-3181563-A1 | CONDENSED 11-MEMBER RING COMPOUND AND AGRICULTURE AND HORTICULTURAL FUNGICIDE COMPRISING SAME | SDS Biotech K. K. (JP) | 2017-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170231226-A1 | FUSED 11-MEMBERED COMPOUNDS AND AGRICULTURAL/HORTICULTURAL FUNGICIDES CONTAINING THEM | CYP51A1, CYP4Z1, ERG28 | CYP2D6 498/4885MEN1 540/4885CYP1A2 99/4885 |
| US-10104891-B2 | Fused 11-membered compounds and agricultural/horticultural fungicides containing them | CYP51A1, CYP4Z1, ERG28 | CYP2D6 498/4885MEN1 540/4885CYP1A2 99/4885 |
| US-20180235225-A1 | FUSED 11-MEMBERED COMPOUNDS AND AGRICULTURAL/HORTICULTURAL FUNGICIDES CONTAINING THEM | CYP51A1, CYP4Z1, ERG28 | CYP2D6 498/4885MEN1 540/4885CYP1A2 99/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.