SCHEMBL18979056

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8507022	0.83	HRH3 (0.55)	SIGMAR1HRH3KCNH2SLC6A3HTR2C
	SCHEMBL3987646	0.83	HRH3 (0.69)	SIGMAR1HRH3KCNH2SLC6A3
	SCHEMBL30446884	0.81	CA2 (0.57)	—
	SCHEMBL4117753	0.78	HRH1 (0.67)	HRH1SIGMAR1SCN5AHRH3LTA4H
	SCHEMBL18917604	0.77	LTA4H (0.75)	HRH1SIGMAR1SCN5AHRH3LTA4H
	SCHEMBL4993786	0.77	HRH3 (0.77)	HRH1SIGMAR1HRH3KCNH2
	SCHEMBL22561783	0.77	HRH3 (0.74)	HRH1SIGMAR1SCN5AHRH3KCNH2
	SCHEMBL4991238	0.77	HRH1 (0.70)	HRH1SIGMAR1SCN5AHRH3LTA4H
	SCHEMBL10642989	0.77	HRH1 (0.60)	HRH1SIGMAR1SCN5AHRH3LTA4H
	SCHEMBL9625455	0.77	HRH1 (0.60)	HRH1SIGMAR1SCN5AHRH3LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.