SCHEMBL18917604

SCHEMBL18917604

c1cc(CCCN2CCCC2)ccc1CCCN1CCCC1

nearest known ligand 0.77

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.75
SIGMAR1 Q99720 4/20 0.70
HRH1 P35367 2/20 0.69
HRH3 Q9Y5N1 7/20 0.65
L3MBTL3 Q96JM7 2/20 0.63
L3MBTL1 Q9Y468 2/20 0.63
MBTD1 Q05BQ5 1/20 0.63
SLC6A3 Q01959 3/20 0.59
SLC6A4 P31645 2/20 0.59
DRD2 P14416 1/20 0.59
CHRM2 P08172 1/20 0.59
ADRA2C P18825 1/20 0.59
SLC6A2 P23975 1/20 0.59
KCNH2 Q12809 1/20 0.59
CACNA1C Q13936 1/20 0.59
SCN5A Q14524 1/20 0.59
GRIN2B Q13224 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7923386 0.90 LTA4H (0.64) LTA4HSIGMAR1HRH1HRH3L3MBTL3
SCHEMBL20382580 0.90 LTA4H (0.86) LTA4HSIGMAR1HRH3SLC6A3GRIN2B
SCHEMBL7997735 0.90 SIGMAR1 (0.65) LTA4HSIGMAR1HRH1HRH3L3MBTL3
SCHEMBL7982901 0.90 HRH3 (0.73) LTA4HSIGMAR1HRH1HRH3L3MBTL3
SCHEMBL14549517 0.90 LTA4H (0.64) LTA4HSIGMAR1HRH1HRH3L3MBTL3
SCHEMBL11955057 0.90 SIGMAR1 (0.65) LTA4HSIGMAR1HRH1HRH3L3MBTL3
SCHEMBL2326201 0.90 LTA4H (0.64) LTA4HSIGMAR1HRH1HRH3L3MBTL3
SCHEMBL14501468 0.90 HRH1 (0.86) LTA4HSIGMAR1HRH1HRH3L3MBTL3
SCHEMBL22813547 0.90 SCN5A (0.71) LTA4HSIGMAR1HRH1HRH3SLC6A3
SCHEMBL5302082 0.89 LTA4H (0.86) LTA4HSIGMAR1HRH3SLC6A3GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108290749-B Novel synthetic crystalline EMM-28 material, its preparation and use 埃克森美孚科技工程公司 2022-06-24 CN disclosed
US-20220023827-A1 EMM-41 Composition, Methods of Making and Uses Thereof EXXONMOBIL RES & ENG CO (US) 2022-01-27 US disclosed
EP-3383796-B1 EMM-28, A NOVEL SYNTHETIC CRYSTALLINE MATERIAL, ITS PREPARATION AND USE EXXONMOBIL RES & ENG CO (US) 2020-09-16 EP disclosed
EP-3383796-B1 EMM-28, A NOVEL SYNTHETIC CRYSTALLINE MATERIAL, ITS PREPARATION AND USE EXXONMOBIL RES & ENG CO (US) 2020-09-16 EP disclosed
US-10597300-B2 EMM-28, a novel synthetic crystalline material, its preparation and use EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-03-24 US disclosed
US-20190218106-A1 EMM-28, A NOVEL SYNTHETIC CRYSTALLINE MATERIAL, ITS PREPARATION AND USE EXXONMOBIL RES & ENG CO (US) 2019-07-18 US disclosed
US-20190218106-A1 EMM-28, A NOVEL SYNTHETIC CRYSTALLINE MATERIAL, ITS PREPARATION AND USE EXXONMOBIL RES & ENG CO (US) 2019-07-18 US disclosed
US-10252918-B2 EMM-28, a novel synthetic crystalline material, its preparation and use EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2019-04-09 US disclosed
US-10252918-B2 EMM-28, a novel synthetic crystalline material, its preparation and use EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2019-04-09 US disclosed
EP-3383796-A1 EMM-28, A NOVEL SYNTHETIC CRYSTALLINE MATERIAL, ITS PREPARATION AND USE Exxonmobil Research And Engineering Company (US) 2018-10-10 EP disclosed
WO-2017095705-A1 EMM-28, A NOVEL SYNTHETIC CRYSTALLINE MATERIAL, ITS PREPARATION AND USE EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2017-06-08 WO disclosed
US-20170158521-A1 EMM-28, A NOVEL SYNTHETIC CRYSTALLINE MATERIAL, ITS PREPARATION AND USE EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2017-06-08 US disclosed
US-20170158521-A1 EMM-28, A NOVEL SYNTHETIC CRYSTALLINE MATERIAL, ITS PREPARATION AND USE EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2017-06-08 US disclosed
US-20170158521-A1 EMM-28, A NOVEL SYNTHETIC CRYSTALLINE MATERIAL, ITS PREPARATION AND USE EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2017-06-08 US disclosed
WO-2017095705-A1 EMM-28, A NOVEL SYNTHETIC CRYSTALLINE MATERIAL, ITS PREPARATION AND USE EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2017-06-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220023827-A1 EMM-41 Composition, Methods of Making and Uses Thereof CD14, CD68, MASP2 LTA4H 1757/4885SIGMAR1 4161/4885HRH1 4159/4885
US-10597300-B2 EMM-28, a novel synthetic crystalline material, its preparation and use CD14, ERG28, DAP3 LTA4H 3486/4885SIGMAR1 3782/4885HRH1 2899/4885
US-10252918-B2 EMM-28, a novel synthetic crystalline material, its preparation and use CD14, ERG28, DAP3 LTA4H 3486/4885SIGMAR1 3782/4885HRH1 2899/4885
US-20170158521-A1 EMM-28, A NOVEL SYNTHETIC CRYSTALLINE MATERIAL, ITS PREPARATION AND USE CD14, ERG28, DAP3 LTA4H 3486/4885SIGMAR1 3782/4885HRH1 2899/4885
US-20190218106-A1 EMM-28, A NOVEL SYNTHETIC CRYSTALLINE MATERIAL, ITS PREPARATION AND USE CD14, ERG28, DAP3 LTA4H 3486/4885SIGMAR1 3782/4885HRH1 2899/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.