SCHEMBL18979134

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19219730	0.95	MAPT (0.48)	TP53GAAMAPTPOLBPTGDR2
	SCHEMBL23169087	0.85	DDR1 (0.37)	TP53GAAMAPTPOLBPTGDR2
	SCHEMBL19017496	0.83	MC4R (0.38)	POLBPTGDR2DDR1ALOX5APFEN1
	SCHEMBL19017565	0.81	DDR1 (0.37)	GAAMAPTPOLBPTGDR2DDR1
	SCHEMBL18979181	0.80	HSD11B1 (0.50)	TP53GAAMAPTPOLBDYRK1A
	SCHEMBL30843064	0.80	MAPT (0.50)	TP53GAAMAPTPOLBDYRK1A
	SCHEMBL20544023	0.80	DDR1 (0.34)	GAAMAPTPOLBPTGDR2DDR1
	SCHEMBL20544024	0.80	DDR1 (0.34)	GAAMAPTPOLBPTGDR2DDR1
	SCHEMBL18751256	0.78	TP53 (0.44)	TP53GAAMAPTPOLBPTGDR2
	SCHEMBL23169086	0.78	S1PR1 (0.34)	GAAPTGDR2DDR1ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.