Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSH | P09668 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1895680 | 0.92 | KMT2A (0.38) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| SCHEMBL1902146 | 0.87 | ALDH1A1 (0.37) | ALDH1A1CYP3A4CA2TSHRLMNA | |
| SCHEMBL985791 | 0.81 | THRA (0.48) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| SCHEMBL1901143 | 0.81 | KMT2A (0.42) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| SCHEMBL1897182 | 0.80 | ALDH1A1 (0.40) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| SCHEMBL1901579 | 0.79 | ALDH1A1 (0.40) | ALDH1A1CYP3A4CA2TSHRLMNA | |
| SCHEMBL9251505 | 0.79 | CYP3A4 (0.44) | ALDH1A1CYP3A4TSHRTDP1L3MBTL1 | |
| SCHEMBL8094597 | 0.78 | ALDH1A1 (0.41) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| SCHEMBL8100398 | 0.78 | ALDH1A1 (0.41) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| SCHEMBL1900161 | 0.75 | TSHR (0.47) | ALDH1A1CYP3A4TSHRTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110101503-A1 | HYPERBRANCHED POLYMER SYNTHESIZING METHOD, HYPERBRANCHED POLYMER, RESIST COMPOSITION, SEMICONDUCTOR INTEGRATED CIRCUIT, AND SEMICONDUCTOR INTEGRATED CIRCUIT FABRICATION METHOD | LION CORPORATION (JP) | 2011-05-05 | — | — | US | disclosed |