SCHEMBL18980937

SCHEMBL18980937

OC(COCC(O)Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.55
CA2 P00918 1/20 0.55
CA7 P43166 1/20 0.55
CA9 Q16790 1/20 0.55
KDM4E B2RXH2 1/20 0.48
TRPA1 O75762 2/20 0.47
SRR Q9GZT4 2/20 0.47
CYP1A2 P05177 1/20 0.45
TSHR P16473 2/20 0.45
EPHX1 P07099 1/20 0.44
MAPT P10636 1/20 0.44
MAPK1 P28482 1/20 0.44
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23258692 0.90 CA1 (0.70) CA1CA2CA7CA9CYP1A2
SCHEMBL3837560 0.86 CA1 (0.47) CA1CA2CA7CA9KDM4E
SCHEMBL1261651 0.84 TRPA1 (0.46) CA1CA2CA7CA9TRPA1
SCHEMBL1170181 0.83 CA1 (0.45) CA1CA2CA7CA9KDM4E
SCHEMBL20958127 0.83 CA1 (0.45) CA1CA2CA7CA9KDM4E
SCHEMBL1833635 0.83 TRPA1 (0.55) TRPA1SRRCYP1A2TSHREPHX1
SCHEMBL5808513 0.83 MAPT (0.55) CA1CA2CA7CA9TRPA1
SCHEMBL17680423 0.80 CA1 (0.58) CA1CA2CA7CA9TSHR
Ammonia Solution, Strong SCHEMBL29021310 0.80 TRPA1 (0.53) TRPA1SRRCYP1A2TSHREPHX1
SCHEMBL10746617 0.79 CA1 (0.57) CA1CA2CA7CA9CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250282958-A1 Curable Photochromic Composition Including a Segmented Polymer TRANSITIONS OPTICAL, LTD. (IE) 2025-09-11 US disclosed
EP-4562458-A1 CURABLE PHOTOCHROMIC COMPOSITIONS INCLUDING HYDRAZIDE AND CARBONYL FUNCTIONAL COMPONENTS Transitions Optical, Ltd. (IE) 2025-06-04 EP disclosed
CN-119895299-A Curable photochromic compositions comprising a hydrazide and a carbonyl functional component 全视线光学有限公司 2025-04-25 CN disclosed
EP-4514918-A1 CURABLE PHOTOCHROMIC COMPOSITION INCLUDING A SEGMENTED POLYMER Transitions Optical, Ltd. (IE) 2025-03-05 EP disclosed
CN-119137238-A Curable photochromic composition comprising segmented polymer 光学转变有限公司 2024-12-13 CN disclosed
WO-2024022586-A1 CURABLE PHOTOCHROMIC COMPOSITIONS INCLUDING HYDRAZIDE AND CARBONYL FUNCTIONAL COMPONENTS TRANSITIONS OPTICAL, LTD. (IE) 2024-02-01 WO disclosed
WO-2023208357-A1 CURABLE PHOTOCHROMIC COMPOSITION INCLUDING A SEGMENTED POLYMER TRANSITIONS OPTICAL, LTD. (IE) 2023-11-02 WO disclosed
EP-3986371-A1 PRODUCT FOR DYEING KERATINOUS MATERIAL, CONTAINING AMINOSILICONE, A CHROMOPHORIC COMPOUND, PRESERVATIVE AND ETHOXYLATED FATTY ALCOHOL Henkel AG & Co. KGaA (DE) 2022-04-27 EP disclosed
EP-3986360-A1 PRODUCT FOR DYEING KERATINOUS MATERIAL, CONTAINING AMINOSILICONE, A CHROMOPHORIC COMPOUND, PRESERVATIVE AND A FATTY CONSTITUENT Henkel AG & Co. KGaA (DE) 2022-04-27 EP disclosed
CN-113993504-A Agent for colouring keratin materials comprising an aminopolysiloxane, a colouring compound, a preservative and an ethoxylated fatty alcohol 汉高股份有限及两合公司 2022-01-28 CN disclosed
WO-2020254008-A1 PRODUCT FOR DYEING KERATINOUS MATERIAL, CONTAINING AMINOSILICONE, A CHROMOPHORIC COMPOUND, PRESERVATIVE AND ETHOXYLATED FATTY ALCOHOL HENKEL AG & CO. KGAA (DE) 2020-12-24 WO disclosed
WO-2020254102-A1 PRODUCT FOR DYEING KERATINOUS MATERIAL, CONTAINING AMINOSILICONE, A CHROMOPHORIC COMPOUND, PRESERVATIVE AND A FATTY CONSTITUENT HENKEL AG & CO. KGAA (DE) 2020-12-24 WO disclosed
US-10328001-B2 Combinations of preservatives for hair dyes HENKEL AG & CO. KGAA (DE) 2019-06-25 US disclosed
US-9999582-B2 Combinations of preservatives for hair colors HENKEL AG & CO. KGAA (DE) 2018-06-19 US disclosed
US-20170172876-A1 COMBINATIONS OF PRESERVATIVES FOR HAIR COLORS HENKEL AG & CO. KGAA (DE) 2017-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170172876-A1 COMBINATIONS OF PRESERVATIVES FOR HAIR COLORS HTR6, HRH4, HAAO CA1 1309/4885CA2 926/4885CA7 1317/4885
US-10328001-B2 Combinations of preservatives for hair dyes KRT18, SORD, SUCLG1 CA1 1624/4885CA2 875/4885CA7 2048/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.