SCHEMBL1898144

SCHEMBL1898144

C=CC(=O)OC(O)Cc1cccc(C(=O)O)c1C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 2/20 0.36
PPARA Q07869 2/20 0.36
FOLH1 Q04609 5/20 0.36
ALDH1A1 P00352 3/20 0.33
HMGB1 P09429 1/20 0.33
THRB P10828 2/20 0.33
KDM4E B2RXH2 2/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
KMT2A Q03164 2/20 0.32
CLCN2 P51788 1/20 0.31
PBRM1 Q86U86 1/20 0.31
PTK2B Q14289 1/20 0.31
EP300 Q09472 1/20 0.31
KAT2B Q92831 1/20 0.31
KAT5 Q92993 1/20 0.31
KAT8 Q9H7Z6 1/20 0.31
THRA P10827 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4663492 0.88 FOLH1 (0.37) PPARGPPARAFOLH1ALDH1A1HMGB1
SCHEMBL690261 0.85 PRKCG (0.36) PPARGPPARAFOLH1ALDH1A1HMGB1
SCHEMBL6567060 0.83 CLCN2 (0.35) PPARGPPARAFOLH1ALDH1A1THRB
SCHEMBL3774107 0.82 PRKCG (0.34) PPARGPPARAFOLH1ALDH1A1HMGB1
SCHEMBL9420515 0.82 THRB (0.37) PPARGPPARAFOLH1ALDH1A1HMGB1
SCHEMBL57688 0.80 THRB (0.41) FOLH1ALDH1A1HMGB1THRBKDM4E
SCHEMBL28531604 0.79 THRB (0.43) FOLH1ALDH1A1HMGB1THRBKDM4E
SCHEMBL22749435 0.78 KMT2A (0.34) PPARGPPARAALDH1A1THRBKMT2A
SCHEMBL587392 0.76 TSHR (0.38) FOLH1ALDH1A1THRB
SCHEMBL6558527 0.76 FOLH1 (0.45) FOLH1ALDH1A1HMGB1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2322986-B1 LIGHT-MODULATING FILM HITACHI CHEMICAL CO LTD (JP) 2019-06-26 EP disclosed
US-10156767-B2 Light control film HITACHI CHEMICAL COMPANY, LTD. (JP) 2018-12-18 US disclosed
CN-104471005-A Adhesive composition for optical film LG HAUSYS LTD 2015-03-25 CN disclosed
CN-1749858-B Method for manufacturing a flexographic printing master AGFA GEVAERT 2012-01-04 CN disclosed
CN-1749856-B Curable jettable liquid for flexography AGFA GEVAERT 2011-10-19 CN disclosed
US-20110143131-A1 LIGHT CONTROL FILM GAUZY LTD (IL) 2011-06-16 US disclosed
EP-2322986-A1 LIGHT-MODULATING FILM Hitachi Chemical Company, Ltd. (JP) 2011-05-18 EP disclosed
CN-1749858-A Method for manufacturing a flexographic printing master AGFA GEVAERT (BE) 2006-03-22 CN disclosed
CN-1749856-A Curable jettable liquid for flexography AGFA GEVAERT (BE) 2006-03-22 CN disclosed