SCHEMBL6567060

SCHEMBL6567060

C=CC(=O)OC(CC)Cc1cccc(C(=O)O)c1C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CLCN2 P51788 1/20 0.35
POLB P06746 1/20 0.35
FOLH1 Q04609 2/20 0.34
CTSL P07711 2/20 0.34
CTSB P07858 2/20 0.34
CTSK P43235 2/20 0.34
THRA P10827 1/20 0.34
THRB P10828 1/20 0.34
PPARA Q07869 3/20 0.33
PPARG P37231 2/20 0.33
PRKCG P05129 1/20 0.33
PRKCB P05771 1/20 0.33
PRKCA P17252 1/20 0.33
PRKCH P24723 1/20 0.33
PRKCE Q02156 1/20 0.33
PRKCD Q05655 1/20 0.33
SLC37A4 O43826 1/20 0.33
ALDH1A1 P00352 2/20 0.32
BID P55957 3/20 0.32
MCL1 Q07820 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9507554 0.91 AKR1C3 (0.36) CLCN2POLBCTSLCTSBCTSK
SCHEMBL3774107 0.86 PRKCG (0.34) FOLH1THRATHRBPPARAPPARG
SCHEMBL690261 0.85 PRKCG (0.36) CLCN2FOLH1THRATHRBPPARA
SCHEMBL4663492 0.84 FOLH1 (0.37) CLCN2FOLH1THRATHRBPPARA
SCHEMBL1898144 0.83 PPARG (0.36) CLCN2FOLH1THRATHRBPPARA
SCHEMBL610158 0.82 SLC37A4 (0.35) CLCN2POLBFOLH1CTSLCTSB
SCHEMBL23121518 0.80 SLC37A4 (0.43) CLCN2POLBTHRBPPARAPPARG
SCHEMBL1564579 0.79 HCAR2 (0.38) PRKCGPRKCBPRKCAPRKCHPRKCE
SCHEMBL27881870 0.77 ALDH1A1 (0.33) THRATHRBPPARAPPARGALDH1A1
SCHEMBL9420515 0.76 THRB (0.37) FOLH1THRBPPARAPPARGSLC37A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1399489-A1 METHOD FOR PRODUCING POLYMER COMPOSITIONS, POLYMER COMPOSITIONS OBTAINED BY USING THIS METHOD, AND THE USE THEREOF Rohmax Additives GmbH (DE) 2004-03-24 EP disclosed
WO-2002096959-A1 METHOD FOR PRODUCING POLYMER COMPOSITIONS, POLYMER COMPOSITIONS OBTAINED BY USING THIS METHOD, AND THE USE THEREOF ROHMAX ADDITIVES GMBH (DE) 2002-12-05 WO disclosed