Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | NDUFS8 | O00217 | 1/20 | 0.47 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.47 |
| ▸ | NDUFAB1 | O14561 | 1/20 | 0.47 |
| ▸ | NDUFA1 | O15239 | 1/20 | 0.47 |
| ▸ | NDUFS4 | O43181 | 1/20 | 0.47 |
| ▸ | NDUFB5 | O43674 | 1/20 | 0.47 |
| ▸ | NDUFB3 | O43676 | 1/20 | 0.47 |
| ▸ | NDUFC1 | O43677 | 1/20 | 0.47 |
| ▸ | NDUFA2 | O43678 | 1/20 | 0.47 |
| ▸ | NDUFS5 | O43920 | 1/20 | 0.47 |
| ▸ | NDUFS7 | O75251 | 1/20 | 0.47 |
| ▸ | NDUFS2 | O75306 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18985197 | 0.82 | MEN1 (0.55) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL447661 | 0.78 | SMN1; SMN2 (0.50) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL447662 | 0.78 | SMN1; SMN2 (0.50) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL4251119 | 0.77 | SMN1; SMN2 (0.48) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL19003362 | 0.77 | RAB9A (0.46) | MAPTNPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL19003307 | 0.73 | EGFR (0.60) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL19003313 | 0.73 | SAE1 (0.46) | MAPTNPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL19003358 | 0.72 | EGFR (0.44) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL19414167 | 0.71 | MAPT (0.62) | MAPTRAB9ASMN1; SMN2NDUFS8COXFA4 | |
| SCHEMBL12001375 | 0.69 | ACACB (0.80) | ACACBMAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | claimed |
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |