Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18985197 | 0.90 | MEN1 (0.55) | SAE1UBA2EGFRMEN1KMT2A | |
| SCHEMBL19003307 | 0.87 | EGFR (0.60) | SAE1UBA2EGFRMEN1KMT2A | |
| SCHEMBL19003274 | 0.86 | MMP1 (0.58) | EGFRMEN1KMT2ALMNANPC1 | |
| SCHEMBL19003279 | 0.83 | ALDH1A1 (0.47) | EGFRMEN1KMT2ALMNANPSR1 | |
| SCHEMBL18985271 | 0.80 | CA12 (0.54) | EGFRMEN1KMT2ALMNANPC1 | |
| SCHEMBL19003250 | 0.79 | MAPT (0.51) | EGFRMEN1KMT2ALMNANPC1 | |
| SCHEMBL19003310 | 0.79 | ALDH1A1 (0.59) | EGFRMEN1KMT2ALMNANPC1 | |
| SCHEMBL19003283 | 0.77 | RAB9A (0.52) | EGFRMEN1KMT2ALMNANPC1 | |
| SCHEMBL19003248 | 0.77 | LMNA (0.56) | EGFRMEN1KMT2ALMNANPC1 | |
| SCHEMBL19003260 | 0.76 | RAB9A (0.67) | MEN1KMT2ALMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |