Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18985197 | 0.84 | MEN1 (0.55) | RAB9ASMN1; SMN2NPC1LMNANPSR1 | |
| SCHEMBL19003358 | 0.81 | EGFR (0.44) | RAB9ASMN1; SMN2NPC1LMNANPSR1 | |
| SCHEMBL18985292 | 0.80 | HDAC8 (0.54) | RAB9ASMN1; SMN2NPC1LMNANFKB1 | |
| SCHEMBL19003360 | 0.78 | HDAC1 (0.46) | RAB9ASMN1; SMN2NPC1LMNANFKB1 | |
| SCHEMBL18985229 | 0.77 | ACACB (0.50) | RAB9ASMN1; SMN2NPC1LMNANFKB1 | |
| SCHEMBL19003307 | 0.75 | EGFR (0.60) | RAB9ASMN1; SMN2NPC1LMNAALDH1A1 | |
| SCHEMBL19003313 | 0.75 | SAE1 (0.46) | RAB9ASMN1; SMN2NPC1LMNANFKB1 | |
| SCHEMBL19003274 | 0.71 | MMP1 (0.58) | RAB9ASMN1; SMN2NPC1LMNANFKB1 | |
| SCHEMBL29806205 | 0.69 | RAB9A (0.52) | RAB9ASMN1; SMN2NPC1LMNANFKB1 | |
| SCHEMBL19003273 | 0.69 | MEN1 (0.55) | RAB9ASMN1; SMN2NPC1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |