Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19020239 | 0.95 | ALDH1A1 (0.69) | ALDH1A1NPC1RAB9ACYP1A2CYP2C9 | |
| SCHEMBL19020392 | 0.86 | ALDH1A1 (0.61) | ALDH1A1NPC1RAB9ACYP1A2CYP2C9 | |
| SCHEMBL18988501 | 0.85 | ALDH1A1 (0.63) | ALDH1A1NPC1RAB9ACYP1A2CYP2C9 | |
| SCHEMBL24187380 | 0.80 | TAS1R3 (0.57) | ALDH1A1NPC1RAB9ACYP1A2MAPT | |
| SCHEMBL4542785 | 0.79 | ALDH1A1 (0.85) | ALDH1A1NPC1RAB9ACYP1A2CYP2C9 | |
| SCHEMBL28713814 | 0.79 | ALDH1A1 (0.60) | ALDH1A1NPC1RAB9ACYP1A2CYP2C9 | |
| SCHEMBL31236187 | 0.79 | ALDH1A1 (0.60) | ALDH1A1NPC1RAB9ACYP1A2CYP2C9 | |
| SCHEMBL19020238 | 0.77 | ALDH1A1 (0.56) | ALDH1A1CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL10852085 | 0.77 | ALDH1A1 (0.82) | ALDH1A1NPC1RAB9ACYP1A2CYP2C9 | |
| SCHEMBL2092853 | 0.77 | ALDH1A1 (0.82) | ALDH1A1NPC1RAB9ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250161291-A1 | SMALL MOLECULES FOR INHIBITING CHEMOKINE ACTIVITY AND/OR CANCER CELLS GROWTH | ALONBIO LTD. (IL) | 2025-05-22 | — | — | US | disclosed |
| US-12233057-B2 | Small molecules for inhibiting chemokine activity and/or cancer cells growth | ALONBIO LTD. (IL) | 2025-02-25 | — | — | US | disclosed |
| EP-3741432-B1 | QUINOLIN-2,4-ONE DERIVATIVES FOR INHIBITING CHEMOKINE ACTIVITY | ALONBIO LTD (IL) | 2023-05-10 | — | — | EP | disclosed |
| US-20220008407-A1 | SMALL MOLECULES FOR INHIBITING CHEMOKINE ACTIVITY AND/OR CANCER CELLS GROWTH | BIOKINE THERAPEUTICS LTD. (IL) | 2022-01-13 | — | — | US | disclosed |
| US-11129824-B2 | Small molecules for inhibiting chemokine activity and/or cancer cells growth | BIOKINE THERAPEUTICS LTD. (IL) | 2021-09-28 | — | — | US | disclosed |
| CN-108699000-B | Small molecules for inhibiting chemokine activity and/or cancer cell growth | 百欧肯治疗有限公司 | 2021-09-21 | — | — | CN | disclosed |
| EP-3741432-A1 | QUINOLIN-2,4-ONE DERIVATIVES FOR INHIBITING CHEMOKINE ACTIVITY | Biokine Therapeutics Ltd. (IL) | 2020-11-25 | — | — | EP | disclosed |
| EP-3390364-B1 | SMALL MOLECULES FOR INHIBITING CHEMOKINE ACTIVITY AND/OR CANCER CELLS GROWTH | BIOKINE THERAPEUTICS LTD (IL) | 2020-07-15 | — | — | EP | disclosed |
| US-20190336492-A1 | SMALL MOLECULES FOR INHIBITING CHEMOKINE ACTIVITY, A KINASE ACTIVITY AND/OR CANCER CELLS GROWTH | ALONBIO LTD. (IL) | 2019-11-07 | — | — | US | disclosed |
| EP-3390364-A1 | SMALL MOLECULES FOR INHIBITING CHEMOKINE ACTIVITY, A KINASE ACTIVITY AND/OR CANCER CELLS GROWTH | Biokine Therapeutics Ltd. (IL) | 2018-10-24 | — | — | EP | disclosed |
| WO-2017103932-A9 | SMALL MOLECULES FOR INHIBITING CHEMOKINE ACTIVITY, A KINASE ACTIVITY AND/OR CANCER CELLS GROWTH | BIOKINE THERAPEUTICS LTD. (IL) | 2017-08-24 | — | — | WO | disclosed |
| WO-2017103932-A1 | SMALL MOLECULES FOR INHIBITING CHEMOKINE ACTIVITY, A KINASE ACTIVITY AND/OR CANCER CELLS GROWTH | BIOKINE THERAPEUTICS LTD. (IL) | 2017-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12233057-B2 | Small molecules for inhibiting chemokine activity and/or cancer cells growth | CCL2, CXCR2, CCL5 | ALDH1A1 2699/4885NPC1 3165/4885RAB9A 641/4885 |
| US-20190336492-A1 | SMALL MOLECULES FOR INHIBITING CHEMOKINE ACTIVITY, A KINASE ACTIVITY AND/OR CANCER CELLS GROWTH | CCL2, CXCR2, CCR2 | ALDH1A1 3101/4885NPC1 3539/4885RAB9A 840/4885 |
| US-20250161291-A1 | SMALL MOLECULES FOR INHIBITING CHEMOKINE ACTIVITY AND/OR CANCER CELLS GROWTH | CCL2, CXCR2, CCL5 | ALDH1A1 2699/4885NPC1 3165/4885RAB9A 641/4885 |
| US-20220008407-A1 | SMALL MOLECULES FOR INHIBITING CHEMOKINE ACTIVITY AND/OR CANCER CELLS GROWTH | CCL2, CXCR2, CCL5 | ALDH1A1 2699/4885NPC1 3165/4885RAB9A 641/4885 |
| US-11129824-B2 | Small molecules for inhibiting chemokine activity and/or cancer cells growth | CCL2, CXCR2, CCL5 | ALDH1A1 2699/4885NPC1 3165/4885RAB9A 641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.