SCHEMBL18988641

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18988725	0.86	MCOLN3 (0.46)	MMP2PKMLMNAL3MBTL1ALDH1A1
	SCHEMBL18988636	0.86	HSD11B1 (0.43)	MMP2MAPTHSD11B1ALDH1A1
	SCHEMBL18988595	0.82	HSD11B1 (0.51)	MMP2CYP3A4CYP2C19PKMHSD11B1
	SCHEMBL2185769	0.78	CYP3A4 (0.48)	TRPA1MMP2CYP3A4CYP2C19PKM
	SCHEMBL2185773	0.78	CYP3A4 (0.48)	TRPA1MMP2CYP3A4CYP2C19PKM
	SCHEMBL7118504	0.77	MAPT (0.52)	TRPA1MMP2CYP3A4CYP2C19PKM
	SCHEMBL7118507	0.77	MAPT (0.52)	TRPA1MMP2CYP3A4CYP2C19PKM
	SCHEMBL7127867	0.76	CA1 (0.50)	TRPA1PKMHTR7L3MBTL1ALDH1A1
	SCHEMBL7127875	0.76	CA1 (0.50)	TRPA1PKMHTR7L3MBTL1ALDH1A1
	SCHEMBL7116937	0.75	CYP3A4 (0.51)	TRPA1CYP3A4CYP2C19HTR7LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.