Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7118507 | 1.00 | MAPT (0.52) | MAPTTDP1TSHRALDH1A1TRPA1 | |
| SCHEMBL7119451 | 0.86 | ELANE (0.51) | ALDH1A1LMNAMMP2L3MBTL1PKM | |
| SCHEMBL7119448 | 0.86 | ELANE (0.51) | ALDH1A1LMNAMMP2L3MBTL1PKM | |
| SCHEMBL7153336 | 0.84 | L3MBTL1 (0.56) | TSHRALDH1A1L3MBTL1CYP3A4CYP2C19 | |
| SCHEMBL7153332 | 0.84 | L3MBTL1 (0.56) | TSHRALDH1A1L3MBTL1CYP3A4CYP2C19 | |
| SCHEMBL7128095 | 0.82 | HSD11B1 (0.52) | ALDH1A1MMP2CYP3A4CYP2C19PKM | |
| SCHEMBL7128097 | 0.82 | HSD11B1 (0.52) | ALDH1A1MMP2CYP3A4CYP2C19PKM | |
| SCHEMBL2185769 | 0.77 | CYP3A4 (0.48) | MAPTTDP1TRPA1HTR7HTR1A | |
| SCHEMBL18988641 | 0.77 | TRPA1 (0.46) | MAPTTDP1ALDH1A1TRPA1HTR7 | |
| SCHEMBL2185773 | 0.77 | CYP3A4 (0.48) | MAPTTDP1TRPA1HTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030153771-A1 | Large scale synthesis of optically pure aziridines | LEXICON PHARMACEUTICALS, INC. | 2003-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153771-A1 | Large scale synthesis of optically pure aziridines | QDPR, AZI2, NISCH | MAPT 4370/4885TDP1 4670/4885TSHR 2216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.