Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 8/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | METTL3 | Q86U44 | 4/20 | 0.33 |
| ▸ | METTL14 | Q9HCE5 | 4/20 | 0.33 |
| ▸ | MAP2 | P11137 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ICMT | O60725 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17397173 | 0.83 | PIK3CD (0.41) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL17397174 | 0.83 | PIK3CD (0.42) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL18988992 | 0.80 | PIK3CD (0.42) | PIK3CDPIK3CAPIK3CBTP53 | |
| SCHEMBL19006238 | 0.80 | PIK3CD (0.43) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL18989289 | 0.77 | PIK3CD (0.41) | PIK3CDPIK3CAPIK3CBLMNAMETTL3 | |
| SCHEMBL18989317 | 0.77 | PIK3CD (0.37) | PIK3CDPIK3CAPIK3CBLMNAMETTL3 | |
| SCHEMBL17397202 | 0.75 | PIK3CA (0.40) | PIK3CDPIK3CAPIK3CB | |
| SCHEMBL17397271 | 0.74 | TAAR1 (0.42) | PIK3CDPIK3CAPIK3CB | |
| SCHEMBL19006144 | 0.73 | PIK3CD (0.39) | PIK3CDPIK3CAPIK3CB | |
| SCHEMBL17397122 | 0.72 | TAAR1 (0.37) | PIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103825-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | LUPIN LIMITED (IN) | 2017-06-22 | — | — | WO | disclosed |