Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGT1 | P19440 | 1/20 | 0.41 |
| ▸ | ARG1 | P05089 | 1/20 | 0.37 |
| ▸ | ARG2 | P78540 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30473641 | 0.83 | DGAT1 (0.40) | CYP2D6DGAT1 | |
| SCHEMBL2916154 | 0.83 | STING1 (0.33) | CYP2D6DGAT1 | |
| SCHEMBL3798958 | 0.83 | CYP2D6 (0.34) | GGT1CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL27568297 | 0.81 | TSHR (0.35) | GGT1CYP2D6TSHRCYP2C19HIF1A | |
| Hydrochloric Acid SCHEMBL10276467 | 0.81 | KDM4E (0.34) | GGT1CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL31238586 | 0.79 | HDAC3 (0.37) | CYP2D6KMT2ATDP1DGAT1 | |
| SCHEMBL7826803 | 0.79 | DGAT1 (0.34) | CYP2D6KDM4ETDP1DGAT1 | |
| SCHEMBL29212940 | 0.79 | GGT1 (0.47) | GGT1ARG1ARG2BLMCYP2D6 | |
| SCHEMBL27718963 | 0.79 | CYP2D6 (0.32) | GGT1CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL8395320 | 0.79 | DGAT1 (0.47) | CYP2D6TSHRTDP1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250352662-A1 | ANTIBODY DRUG CONJUGATES COMPRISING STING AGONISTS | MERSANA THERAPEUTICS INC (US) | 2025-11-20 | — | — | US | disclosed |
| US-12440576-B2 | Antibody drug conjugates comprising sting agonists | MERSANA THERAPEUTICS, INC. (US) | 2025-10-14 | — | — | US | disclosed |
| US-12156870-B2 | Antibody drug conjugates comprising sting agonists | MERSANA THERAPEUTICS, INC. (US) | 2024-12-03 | — | — | US | disclosed |
| US-20240368150-A1 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES FOR THE TREATMENT OF CANCER | HOFFMANN-LA ROCHE INC. (US) | 2024-11-07 | — | — | US | disclosed |
| US-20230321048-A1 | ANTIBODY DRUG CONJUGATES COMPRISING STING AGONISTS | MERSANA THERAPEUTICS, INC. | 2023-10-12 | — | — | US | disclosed |
| EP-4218826-A2 | ANTIBODY DRUG CONJUGATES COMPRISING STING AGONISTS | Mersana Therapeutics, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| US-20230172910-A1 | ANTIBODY DRUG CONJUGATES COMPRISING STING AGONISTS | MERSANA THERAPEUTICS, INC. | 2023-06-08 | — | — | US | disclosed |
| CN-116196435-A | Antibody drug conjugates comprising STING agonists | 梅尔莎纳医疗公司 | 2023-06-02 | — | — | CN | disclosed |
| US-20230136562-A1 | SPIROUREA DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-05-04 | — | — | US | disclosed |
| EP-4168399-A1 | COMPOUNDS AND THEIR USES AS MIF INHIBITORS | Nanjing Immunophage Biotech Co., Ltd. (CN) | 2023-04-26 | — | — | EP | disclosed |
| WO-1997015573-A1 | PROCESS FOR THE PREPARATION OF A GROWTH HORMONE SECRETAGOGUE | MERCK & CO., INC. (US) | 1997-05-01 | — | — | WO | disclosed |
| WO-1997015574-A1 | POLYMORPHIC FORMS OF A GROWTH HORMONE SECRETAGOGUE | MERCK & CO., INC. (US) | 1997-05-01 | — | — | WO | disclosed |
| WO-1996031515-A1 | SELECTED SOLUBLE ESTERS OF HYDROXYL-CONTAINING INDOLOCARBAZOLES | CEPHALON, INC. (US) | 1996-10-10 | — | — | WO | disclosed |
| EP-0672055-A1 | NEUROPEPTIDE Y ANTAGONISTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| EP-0659181-A1 | SULFONAMIDE INHIBITORS OF HIV-ASPARTYL PROTEASE | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1995-06-28 | — | — | EP | disclosed |
| WO-1994005639-A1 | SULFONAMIDE INHIBITORS OF HIV-ASPARTYL PROTEASE | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1994-03-17 | — | — | WO | disclosed |
| WO-1994000486-A1 | NEUROPEPTIDE Y ANTAGONISTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-01-06 | — | — | WO | disclosed |
| US-4430265-A | IMMUNOSTIMULATORY ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-02-07 | — | — | US | disclosed |
| EP-0002677-B1 | GLUCOSAMINE-PEPTIDE DERIVATIVES AND THEIR PHARMACEUTICAL COMPOSITIONS | Takeda Chemical Industries, Ltd. (JP) | 1982-10-13 | — | — | EP | disclosed |
| US-4338305-A | LUTEINIZING HORMONE RELEASING HORMONE; CONTRACEPTIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12156870-B2 | Antibody drug conjugates comprising sting agonists | STING1, CGAS, IFNAR1 | GGT1 1021/4885ARG1 2084/4885ARG2 2020/4885 |
| US-12440576-B2 | Antibody drug conjugates comprising sting agonists | STING1, CGAS, IFNAR1 | GGT1 1021/4885ARG1 2084/4885ARG2 2020/4885 |
| US-20240368150-A1 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES FOR THE TREATMENT OF CANCER | BICRA, BRD4, CNR1 | GGT1 4644/4885ARG1 578/4885ARG2 760/4885 |
| US-20230321048-A1 | ANTIBODY DRUG CONJUGATES COMPRISING STING AGONISTS | STING1, CGAS, IFNAR1 | GGT1 1021/4885ARG1 2084/4885ARG2 2020/4885 |
| US-20230172910-A1 | ANTIBODY DRUG CONJUGATES COMPRISING STING AGONISTS | STING1, CGAS, IFNAR1 | GGT1 1021/4885ARG1 2084/4885ARG2 2020/4885 |
| US-20250352662-A1 | ANTIBODY DRUG CONJUGATES COMPRISING STING AGONISTS | STING1, CGAS, IFNAR1 | GGT1 1021/4885ARG1 2084/4885ARG2 2020/4885 |
| US-20230136562-A1 | SPIROUREA DERIVATIVES | KCNA7, PKD2, KCNN3 | GGT1 3984/4885ARG1 3646/4885ARG2 3342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.