Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17059404 | 0.92 | HMGB1 (0.47) | KDM4EALDH1A1HMGB1HPGDTSHR | |
| SCHEMBL22620281 | 0.88 | BRPF1 (0.42) | SMN1; SMN2KDM4ELMNAALDH1A1HPGD | |
| SCHEMBL8582286 | 0.81 | LMNA (0.42) | SMN1; SMN2KDM4ELMNAALDH1A1THRB | |
| SCHEMBL17059407 | 0.80 | HMGB1 (0.41) | SMN1; SMN2KDM4ELMNAALDH1A1HMGB1 | |
| SCHEMBL27669069 | 0.79 | HMGB1 (0.55) | SMN1; SMN2KDM4EALDH1A1HMGB1HPGD | |
| SCHEMBL17059422 | 0.77 | HMGB1 (0.53) | SMN1; SMN2KDM4EALDH1A1HMGB1HPGD | |
| SCHEMBL17059414 | 0.77 | TAAR1 (0.41) | SMN1; SMN2KDM4EALDH1A1HMGB1HPGD | |
| SCHEMBL10499032 | 0.76 | GABRA1 (0.48) | SMN1; SMN2KDM4ELMNAALDH1A1THRB | |
| SCHEMBL2904188 | 0.76 | KDM4E (0.43) | SMN1; SMN2KDM4ELMNAALDH1A1HMGB1 | |
| SCHEMBL28482372 | 0.76 | CA5A (0.43) | SMN1; SMN2LMNAKMT2ATSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2325167-A1 | METHOD FOR PRODUCING CARBAMATE COMPOUND | Ube Industries, Ltd. (JP) | 2011-05-25 | — | — | EP | disclosed |