Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.37 |
| ▸ | LOX | P28300 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10202978 | 0.76 | MCHR1 (0.40) | MCHR1ALOX5APFEN1 | |
| SCHEMBL18994470 | 0.70 | CYP1A2 (0.31) | — | |
| SCHEMBL10202933 | 0.70 | TSHR (0.44) | MCHR1 | |
| SCHEMBL18994394 | 0.68 | LNPEP (0.33) | — | |
| SCHEMBL22905267 | 0.68 | ALOX5AP (0.33) | ALOX5APFEN1 | |
| SCHEMBL18994419 | 0.68 | HTR1A (0.38) | MCHR1 | |
| SCHEMBL13028811 | 0.67 | LOXL2 (0.65) | LOXL2LOX | |
| SCHEMBL21227110 | 0.64 | LOXL2 (0.61) | LOXL2LOX | |
| SCHEMBL22837053 | 0.64 | KCNK3 (0.35) | — | |
| SCHEMBL4930812 | 0.64 | LOXL2 (0.59) | LOXL2LOXMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682998-B2 | Fused heterocyclic compounds as ion channel modulators | GILEAD SCIENCES, INC. (US) | 2017-06-20 | — | — | US | disclosed |