SCHEMBL19000669

SCHEMBL19000669

N=c1ccc2c(-c3ccccc3C(=O)OCC(=O)NCCOCCOCCNC(=O)/C=C/c3ccc(O)cc3)c3ccc(N)cc3oc-2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ABCB1 P08183 1/20 0.55
▸ USP2 O75604 2/20 0.54
▸ CFTR P13569 1/20 0.54
▸ PAX8 Q06710 1/20 0.54
▸ ATM Q13315 1/20 0.54
▸ GOPC Q9HD26 1/20 0.54
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ PTGER3 P43115 2/20 0.33
▸ MMP1 P03956 1/20 0.33
▸ MMP2 P08253 1/20 0.33
▸ MMP9 P14780 1/20 0.33
▸ PYGL P06737 1/20 0.32
▸ FOLH1 Q04609 1/20 0.32
▸ CA12 O43570 1/20 0.31
▸ CA1 P00915 1/20 0.31
▸ CA2 P00918 1/20 0.31
▸ CA9 Q16790 1/20 0.31
▸ HTR3A P46098 1/20 0.30
▸ GJA1 P17302 1/20 0.30
▸ GJB2 P29033 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19000673 0.87 USP2 (0.42) USP2ATML3MBTL1PTGER3FOLH1
SCHEMBL19000672 0.83 CA12 (0.40) USP2ATML3MBTL1PTGER3FOLH1
SCHEMBL19000687 0.82 GBA1 (0.44) CA12CA1CA2CA9HTR3A
SCHEMBL19000681 0.80 TGM2 (0.43) USP2
SCHEMBL19000677 0.79 FTO (0.51) USP2L3MBTL1MMP1MMP2MMP9
SCHEMBL27057211 0.77 CA9 (0.45) USP2ATML3MBTL1PTGER3FOLH1
SCHEMBL22007229 0.77 FOLH1 (0.43) USP2ATML3MBTL1PTGER3FOLH1
SCHEMBL12923622 0.76 ABCB1 (0.75) ABCB1USP2CFTRPAX8ATM
SCHEMBL19000694 0.75 USP2 (0.31) USP2
SCHEMBL19000671 0.74 USP2 (0.30) USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3391056-B1 CHROMOGENIC PEROXIDASE SUBSTRATES AGILENT TECHNOLOGIES INC (US) 2024-01-17 — — EP disclosed
US-20230002816-A1 CHROMOGENIC PEROXIDASE SUBSTRATES DAKO DENMARK APS (DK) 2023-01-05 — — US disclosed
US-11466314-B2 Chromogenic peroxidase substrates AGILENT TECHNOLOGIES, INC. (US) 2022-10-11 — — US disclosed
US-20200157613-A1 CHROMOGENIC PEROXIDASE SUBSTRATES DAKO DENMARK APS (DK) 2020-05-21 — — US disclosed
US-20170175178-A1 CHROMOGENIC PEROXIDASE SUBSTRATES DAKO DENMARK APS (DK) 2017-06-22 — — US disclosed
US-20170175178-A1 CHROMOGENIC PEROXIDASE SUBSTRATES DAKO DENMARK APS (DK) 2017-06-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170175178-A1 CHROMOGENIC PEROXIDASE SUBSTRATES MPO, TPO, TYR ABCB1 2422/4885USP2 2528/4885CFTR 3630/4885
US-11466314-B2 Chromogenic peroxidase substrates MPO, TPO, TYR ABCB1 2432/4885USP2 2385/4885CFTR 3727/4885
US-20200157613-A1 CHROMOGENIC PEROXIDASE SUBSTRATES MPO, TPO, TYR ABCB1 2432/4885USP2 2385/4885CFTR 3727/4885
US-20230002816-A1 CHROMOGENIC PEROXIDASE SUBSTRATES MPO, TPO, TYR ABCB1 2432/4885USP2 2385/4885CFTR 3727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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