SCHEMBL19001567

SCHEMBL19001567

CCCCCCc1cc(C)cc(-n2c3ccccc3c3ccc(-c4ncc(Br)c5ccccc45)cc32)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 3/20 0.34
PSEN1 P49768 1/20 0.32
PSEN2 P49810 1/20 0.32
APH1B Q8WW43 1/20 0.32
NCSTN Q92542 1/20 0.32
APH1A Q96BI3 1/20 0.32
PSENEN Q9NZ42 1/20 0.32
MAPT P10636 2/20 0.31
CTSV O60911 1/20 0.31
CTSL P07711 1/20 0.31
TLR7 Q9NYK1 1/20 0.31
RORA P35398 1/20 0.31
RORC P51449 1/20 0.31
RORB Q92753 1/20 0.31
TP53 P04637 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
USP2 O75604 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18987386 0.94 HSD11B1 (0.34) HSD11B1PSEN1PSEN2APH1BNCSTN
SCHEMBL20615092 0.85 KDM4E (0.33) MAPTRXFP1KDM4EALDH1A1GAA
SCHEMBL19006916 0.82 ADORA3 (0.34) HSD11B1MAPTTLR7TP53ALDH1A1
SCHEMBL19001590 0.81 RORA (0.36) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL4546847 0.81 RORA (0.41) HSD11B1PSEN1PSEN2APH1BNCSTN
SCHEMBL18987393 0.78 LPL (0.38) HSD11B1PSEN1PSEN2APH1BNCSTN
SCHEMBL18987135 0.76 ADORA3 (0.35) HSD11B1MAPTTLR7TP53KDM4E
SCHEMBL18987170 0.75 RORA (0.39) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL19001597 0.73 HSD11B1 (0.33) HSD11B1MAPTRAB9ASMN1; SMN2
SCHEMBL4546849 0.71 TP53 (0.37) HSD11B1CTSVCTSLRORARORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3390418-B1 LIGHT-EMITTING COMPOUND CAMBRIDGE DISPLAY TECH LTD (GB) 2020-08-05 EP disclosed
WO-2017103584-A1 LIGHT-EMITTING COMPOUND CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-06-22 WO disclosed
WO-2017103586-A1 LIGHT-EMITTING COMPOSITION CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-06-22 WO disclosed