SCHEMBL19001568

SCHEMBL19001568

Cc1cc(C)cc(-n2c3ccccc3c3ccc(-c4ncc(-c5nc(-c6ccc(C(C)(C)C)cc6)nc(-c6ccc(C(C)(C)C)cc6)n5)c5ccccc45)cc32)c1

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.36
NPSR1 Q6W5P4 3/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPK1 P28482 1/20 0.36
TP53 P04637 4/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
KDM4E B2RXH2 2/20 0.33
LMNA P02545 2/20 0.33
ABCG2 Q9UNQ0 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
PIN1 Q13526 2/20 0.33
POLB P06746 1/20 0.33
KDR P35968 1/20 0.32
NPC1 O15118 2/20 0.31
HTT P42858 1/20 0.31
DGAT1 O75907 1/20 0.30
NR1H4 Q96RI1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19006916 0.88 ADORA3 (0.34) MAPTNPSR1ALDH1A1MAPK1TP53
SCHEMBL18987135 0.83 ADORA3 (0.35) MAPTNPSR1ALDH1A1MAPK1TP53
SCHEMBL20615092 0.77 KDM4E (0.33) MAPTALDH1A1KDM4ERAB9APOLB
SCHEMBL17691581 0.76 TP53 (0.43) MAPTNPSR1ALDH1A1MAPK1TP53
SCHEMBL15248444 0.76 MAPT (0.43) MAPTNPSR1ALDH1A1MAPK1TP53
SCHEMBL16726767 0.76 PTGER4 (0.37) MAPTALDH1A1TP53MEN1KMT2A
SCHEMBL24810553 0.75 ALDH1A1 (0.43) MAPTNPSR1ALDH1A1MAPK1TP53
SCHEMBL16726761 0.74 ALDH1A1 (0.41) MAPTNPSR1ALDH1A1MAPK1TP53
SCHEMBL16726773 0.74 ALDH1A1 (0.41) MAPTNPSR1ALDH1A1MAPK1TP53
SCHEMBL16726770 0.74 ALDH1A1 (0.44) MAPTNPSR1ALDH1A1MAPK1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11214585-B2 Light-emitting composition CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2022-01-04 US disclosed
EP-3390418-B1 LIGHT-EMITTING COMPOUND CAMBRIDGE DISPLAY TECH LTD (GB) 2020-08-05 EP disclosed
US-20190002629-A1 LIGHT-EMITTING COMPOSITION CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2019-01-03 US disclosed
US-20190002488-A1 LIGHT-EMITTING COMPOUND CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2019-01-03 US disclosed
WO-2017103584-A1 LIGHT-EMITTING COMPOUND CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-06-22 WO disclosed
WO-2017103586-A1 LIGHT-EMITTING COMPOSITION CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11214585-B2 Light-emitting composition CRY1, CRY2, ARL1 MAPT 977/4885NPSR1 3503/4885ALDH1A1 908/4885
US-20190002488-A1 LIGHT-EMITTING COMPOUND AR, ARL1, IK MAPT 2235/4885NPSR1 3164/4885ALDH1A1 222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.