SCHEMBL19001705

SCHEMBL19001705

O=C1c2ccccc2-c2cccc(-c3cccc(-c4ccccc4)c3)c21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.58
MEN1 O00255 4/20 0.58
KMT2A Q03164 4/20 0.58
LMNA P02545 3/20 0.58
APAF1 O14727 2/20 0.58
NPC1 O15118 2/20 0.58
THRB P10828 2/20 0.58
HTT P42858 2/20 0.58
RAB9A P51151 2/20 0.58
GALK1 P51570 2/20 0.58
BLM P54132 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
NPSR1 Q6W5P4 2/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
XBP1 P17861 1/20 0.58
PTBP1 P26599 1/20 0.58
SMAD3 P84022 1/20 0.58
ATM Q13315 1/20 0.58
ALDH1A1 P00352 2/20 0.50
ADORA2A P29274 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21498269 0.88 LMNA (0.50) MAPTMEN1KMT2ALMNAAPAF1
SCHEMBL19299526 0.88 NPC1 (0.50) MAPTMEN1KMT2ALMNAAPAF1
SCHEMBL978805 0.88 MAPT (0.57) MAPTMEN1KMT2ALMNAAPAF1
SCHEMBL19299407 0.86 LMNA (0.47) MAPTMEN1KMT2ALMNAAPAF1
SCHEMBL22730653 0.86 MAPT (0.59) MAPTMEN1KMT2ALMNAAPAF1
SCHEMBL19001848 0.85 MAPT (0.53) MAPTMEN1KMT2ALMNAAPAF1
SCHEMBL29595074 0.84 LMNA (0.59) MAPTMEN1KMT2ALMNAAPAF1
SCHEMBL22182158 0.83 TDP2 (0.51) MAPTMEN1KMT2ALMNAAPAF1
SCHEMBL23989075 0.81 MAPT (0.53) MAPTMEN1KMT2ALMNAAPAF1
SCHEMBL19299391 0.81 PTPRC (0.52) MAPTMEN1KMT2ALMNAAPAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3390365-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-04-14 EP disclosed
CN-112390771-A Novel hole transport material with excellent performance and organic electroluminescent device containing material 南京高光半导体材料有限公司 2021-02-23 CN disclosed
WO-2017102063-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2017-06-22 WO disclosed