Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | APAF1 | O14727 | 2/20 | 0.50 |
| ▸ | PTBP1 | P26599 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | GALK1 | P51570 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | SMAD3 | P84022 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PTPRC | P08575 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19001705 | 0.88 | MAPT (0.58) | NPC1RAB9ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL19299391 | 0.85 | PTPRC (0.52) | NPC1RAB9ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL21498269 | 0.84 | LMNA (0.50) | NPC1RAB9ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL19299465 | 0.77 | MEN1 (0.50) | NPC1RAB9ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL24945475 | 0.77 | HSD17B10 (0.62) | NPC1RAB9ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL978805 | 0.77 | MAPT (0.57) | NPC1RAB9ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL22182158 | 0.76 | TDP2 (0.51) | NPC1RAB9ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL16601827 | 0.75 | NPC1 (0.70) | NPC1RAB9ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL17463730 | 0.75 | ALDH1A1 (0.56) | NPC1RAB9ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL19299407 | 0.75 | LMNA (0.47) | NPC1RAB9ASMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3419960-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-07-01 | — | — | EP | disclosed |
| WO-2017144150-A2 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-08-31 | — | — | WO | disclosed |