Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24723588 | 0.88 | ALDH1A1 (0.56) | SIRT1POLBALDH1A1MAPTMEN1 | |
| SCHEMBL27780108 | 0.86 | SIRT1 (0.54) | SIRT1POLBALDH1A1MAPTMEN1 | |
| SCHEMBL231042 | 0.84 | SIRT1 (0.71) | SIRT1POLBALDH1A1MAPTMEN1 | |
| SCHEMBL29435080 | 0.81 | SIRT1 (0.58) | SIRT1POLBALDH1A1MAPTMEN1 | |
| SCHEMBL6937301 | 0.81 | ALDH1A1 (0.55) | SIRT1POLBALDH1A1MAPTMEN1 | |
| SCHEMBL942508 | 0.81 | SIRT1 (0.58) | SIRT1POLBALDH1A1MAPTMEN1 | |
| SCHEMBL23372785 | 0.80 | ALDH1A1 (0.57) | SIRT1POLBALDH1A1MAPTMEN1 | |
| SCHEMBL19847390 | 0.80 | ALDH1A1 (0.52) | SIRT1POLBALDH1A1MAPTMEN1 | |
| SCHEMBL9557894 | 0.80 | MAPT (0.50) | SIRT1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9622183 | 0.79 | ALDH1A1 (0.51) | SIRT1POLBALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496549-B1 | NEW, NON-CRYSTALLISING METHACRYLATE, ITS MANUFACTURE AND APPLICATION | BAYER IP GMBH (DE) | 2014-10-08 | — | — | EP | disclosed |
| EP-2496549-A2 | NOVEL NON-CRYSTALLIZING METHACRYLATES, PRODUCTION AND USE THEREOF | Bayer MaterialScience AG (DE) | 2012-09-12 | — | — | EP | disclosed |
| US-20120219885-A1 | NOVEL NON-CRYSTALLIZING METHACRYLATES, PRODUCTION AND USE THEREOF | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-08-30 | — | — | US | disclosed |
| WO-2011054818-A2 | NOVEL NON-CRYSTALLIZING METHACRYLATES, PRODUCTION AND USE THEREOF | BAYER MATERIALSCIENCE AG (DE) | 2011-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120219885-A1 | NOVEL NON-CRYSTALLIZING METHACRYLATES, PRODUCTION AND USE THEREOF | MEP1A, MMAB, RHOA | SIRT1 4138/4885POLB 3707/4885ALDH1A1 3355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.