SCHEMBL9622183

SCHEMBL9622183

O=C(O)c1ccc(Sc2ccccc2)c(C(=O)O)c1Sc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.51
MAPT P10636 3/20 0.51
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
SIRT1 Q96EB6 1/20 0.46
POLB P06746 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
ALOX15 P16050 1/20 0.39
HPGD P15428 2/20 0.38
BCL2L1 Q07817 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
BLM P54132 1/20 0.36
AKR1C3 P42330 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA4 P22748 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CDC25A P30304 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11688383 0.86 SIRT1 (0.49) ALDH1A1MAPTMEN1KMT2ASIRT1
SCHEMBL942508 0.79 SIRT1 (0.58) ALDH1A1MAPTMEN1KMT2ASIRT1
SCHEMBL1900181 0.79 SIRT1 (0.58) ALDH1A1MAPTMEN1KMT2ASIRT1
SCHEMBL29435080 0.79 SIRT1 (0.58) ALDH1A1MAPTMEN1KMT2ASIRT1
SCHEMBL24723588 0.77 ALDH1A1 (0.56) ALDH1A1MAPTMEN1KMT2ASIRT1
SCHEMBL7542476 0.75 SIRT1 (0.49) ALDH1A1MAPTMEN1KMT2ASIRT1
SCHEMBL9295580 0.74 SIRT1 (0.47) ALDH1A1MAPTMEN1KMT2ASIRT1
SCHEMBL23665075 0.74 ALDH1A1 (0.53) ALDH1A1MAPTMEN1KMT2ASIRT1
SCHEMBL231042 0.74 SIRT1 (0.71) ALDH1A1MAPTMEN1KMT2ASIRT1
SCHEMBL9686145 0.73 CA12 (0.59) ALDH1A1MAPTMEN1KMT2ASIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5128429-A Low temperature block polymerization without randomization RAYCHEM LIMITED (GB) 1992-07-07 US disclosed
EP-0154506-B1 PREPARATION OF ORGANIC POLYMERS RAYCHEM LIMITED (GB) 1992-02-05 EP disclosed
US-4999411-A Polythioethers, polythiocarbonates, polythioamides, polythioimides RAYCHEM LIMITED (GB) 1991-03-12 US disclosed
US-4960835-A ENGINEERING THERMOPLASTICS RAYCHEM LIMITED (GB) 1990-10-02 US disclosed
US-4845179-A CONDENSATION POLYMERIZATION RAYCHEM LIMITED (GB) 1989-07-04 US disclosed
EP-0154506-A2 Preparation of organic polymers RAYCHEM LIMITED (GB) 1985-09-11 EP disclosed