Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 7/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19002147 | 0.81 | MEN1 (0.52) | PDK2ESR1ESR2KDM4ELMNA | |
| SCHEMBL382439 | 0.80 | ESR1 (0.50) | PDK2ESR1ESR2KDM4ELMNA | |
| SCHEMBL29646285 | 0.80 | ESR1 (0.50) | PDK2ESR1ESR2KDM4ELMNA | |
| SCHEMBL29482233 | 0.80 | ESR1 (0.50) | PDK2ESR1ESR2KDM4ELMNA | |
| SCHEMBL13497452 | 0.76 | LMNA (0.50) | PDK2ESR1ESR2APPKDM4E | |
| SCHEMBL21451597 | 0.74 | PDK2 (0.49) | PDK2ESR1ESR2KDM4ELMNA | |
| SCHEMBL26257703 | 0.73 | PDK2 (0.43) | PDK2ESR1ESR2KDM4ELMNA | |
| SCHEMBL13497453 | 0.73 | LMNA (0.47) | PDK2ESR1ESR2APPLMNA | |
| SCHEMBL20741395 | 0.72 | PDK2 (0.51) | PDK2ESR1ESR2KDM4ELMNA | |
| SCHEMBL20795883 | 0.71 | PDK2 (0.50) | PDK2ESR1ESR2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655386-B2 | Polymer having antireflective properties, hardmask composition including the same, process for forming a patterned material layer, and associated device | CHEIL INDUSTRIES, INC. (KR) | 2010-02-02 | — | — | US | disclosed |