Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19002274 | 0.82 | POLB (0.50) | ACMSDIDO1TDO2KDM4EGAA | |
| SCHEMBL9159128 | 0.73 | PIM1 (0.49) | KDM4EGAAPOLBATMALDH1A1 | |
| SCHEMBL9153226 | 0.73 | ATM (0.49) | KDM4EGAAPOLBATMALDH1A1 | |
| SCHEMBL14916341 | 0.71 | PDE9A (0.49) | IDO1TDO2KDM4E | |
| SCHEMBL28901729 | 0.69 | POLB (0.70) | ACMSDKDM4EGAAPOLBATM | |
| SCHEMBL8240673 | 0.66 | CLK4 (0.49) | IDO1CTSSCTSKRXRARXRB | |
| SCHEMBL26997544 | 0.66 | CTSA (0.49) | ALDH1A1CTSSCTSKRXRARXRB | |
| SCHEMBL5352034 | 0.66 | RXRA (0.62) | KDM4EATMALDH1A1CTSSCTSK | |
| SCHEMBL5937494 | 0.66 | ACMSD (0.61) | ACMSDKDM4EGAAPOLBALDH1A1 | |
| SCHEMBL28483299 | 0.66 | ACMSD (0.64) | ACMSDKDM4EGAAPOLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017106552-A1 | POTENTIATORS OF BETA-LACTAM ANTIBIOTICS AND COMBINATION THERAPY | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2017-06-22 | — | — | WO | disclosed |