Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1680997 | 0.80 | KDM4E (0.35) | ALDH1A1KDM4EHSD17B10CCR1CCR5 | |
| SCHEMBL18997065 | 0.79 | NUDT1 (0.40) | NUDT1ADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL6938238 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KDM4EHSD17B10CCR1CCR5 | |
| SCHEMBL21494388 | 0.77 | ADRA2A (0.47) | NUDT1ADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL19122787 | 0.76 | CCR1 (0.43) | ADRA2AADRA2BADRA2CALDH1A1KDM4E | |
| SCHEMBL19122859 | 0.76 | CCR1 (0.43) | ADRA2AADRA2BADRA2CALDH1A1KDM4E | |
| SCHEMBL18726999 | 0.74 | CCR1 (0.41) | ADRA2AADRA2BADRA2CALDH1A1KDM4E | |
| SCHEMBL21900738 | 0.74 | HPGD (0.37) | NUDT1ADRA2AADRA2BADRA2CHTR6 | |
| SCHEMBL26524482 | 0.74 | CCR1 (0.41) | ADRA2AADRA2BADRA2CALDH1A1KDM4E | |
| SCHEMBL4539717 | 0.73 | PKM (0.44) | ALDH1A1KDM4EHSD17B10HDAC6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170174699-A1 | COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE | SHY Therapeutics LLC | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174699-A1 | COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE | MAPK6, MAP3K6, MAPK4 | NUDT1 1968/4885ADRA2A 4315/4885ADRA2B 4143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.