Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | PPME1 | Q9Y570 | 4/20 | 0.47 |
| ▸ | APEH | P13798 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NEK2 | P51955 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11560494 | 0.86 | PPME1 (0.55) | BTKMEN1KMT2AKDM4EPPME1 | |
| SCHEMBL11560496 | 0.86 | PPME1 (0.55) | BTKMEN1KMT2AKDM4EPPME1 | |
| SCHEMBL11563220 | 0.81 | PPME1 (0.57) | BTKMEN1KMT2AKDM4EPPME1 | |
| SCHEMBL8540758 | 0.76 | CYP1A2 (0.58) | MEN1KMT2AKDM4EPPME1ALDH1A1 | |
| SCHEMBL8540762 | 0.76 | CYP1A2 (0.58) | MEN1KMT2AKDM4EPPME1ALDH1A1 | |
| SCHEMBL29289237 | 0.71 | ALDH1A1 (0.65) | MEN1KMT2AKDM4EPPME1ALDH1A1 | |
| SCHEMBL29289241 | 0.71 | ALDH1A1 (0.65) | MEN1KMT2AKDM4EPPME1ALDH1A1 | |
| SCHEMBL4144065 | 0.70 | NEK2 (0.49) | BTKMEN1KMT2AKDM4EPPME1 | |
| SCHEMBL4144063 | 0.70 | NEK2 (0.49) | BTKMEN1KMT2AKDM4EPPME1 | |
| SCHEMBL5439935 | 0.70 | AKR1C3 (0.45) | MEN1KMT2AALDH1A1PTGS2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017106552-A1 | POTENTIATORS OF BETA-LACTAM ANTIBIOTICS AND COMBINATION THERAPY | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2017-06-22 | — | — | WO | disclosed |