Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1A | Q16819 | 1/20 | 0.51 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29565551 | 0.89 | MEP1A (0.53) | MEP1AMEP1BNPC1RAB9AKMT2A | |
| SCHEMBL19049388 | 0.84 | MEP1A (0.52) | MEP1AMEP1BNPC1RAB9AKMT2A | |
| SCHEMBL1379138 | 0.84 | MEP1A (0.52) | MEP1AMEP1BNPC1RAB9AKMT2A | |
| SCHEMBL24160931 | 0.84 | MEP1A (0.56) | MEP1AMEP1BNPC1RAB9AKMT2A | |
| SCHEMBL19002498 | 0.82 | NSD2 (0.56) | NPC1RAB9AKMT2ASLC6A2SLC6A4 | |
| SCHEMBL12505597 | 0.82 | MEP1A (0.56) | MEP1AMEP1BNPC1RAB9AKMT2A | |
| SCHEMBL19049392 | 0.82 | SLC6A2 (0.53) | MEP1AMEP1BNPC1RAB9ASLC6A2 | |
| SCHEMBL19002494 | 0.82 | MEP1A (0.53) | MEP1AMEP1BNPC1RAB9AKMT2A | |
| SCHEMBL17882315 | 0.81 | RIPK1 (0.66) | MEP1AMEP1BHSD17B1HSD17B2RIPK1 | |
| SCHEMBL19002587 | 0.80 | HSD17B1 (0.56) | NPC1RAB9AKMT2AHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170174699-A1 | COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE | SHY Therapeutics LLC | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174699-A1 | COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE | MAPK6, MAP3K6, MAPK4 | MEP1A 3642/4885MEP1B 3538/4885NPC1 2024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.