Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 6/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1368134 | 0.87 | KCNN4 (0.41) | KCNN4TSHRALDH1A1MAPK1CYP1A2 | |
| SCHEMBL21530763 | 0.87 | KCNN4 (0.31) | KCNN4TSHRALDH1A1 | |
| SCHEMBL1326257 | 0.80 | KCNN4 (0.36) | KCNN4TSHRALDH1A1MAPK1CYP1A2 | |
| SCHEMBL11029195 | 0.79 | ALDH1A1 (0.36) | KCNN4TSHRALDH1A1MAPK1ATM | |
| SCHEMBL416260 | 0.78 | KCNN4 (0.47) | KCNN4TSHRALDH1A1MAPK1CYP1A2 | |
| SCHEMBL648242 | 0.78 | HSD17B10 (0.42) | TSHRALDH1A1ATMCYP1A2ALOX15 | |
| SCHEMBL29043512 | 0.76 | KCNN4 (0.57) | KCNN4TSHRALDH1A1MAPK1CYP1A2 | |
| SCHEMBL15660504 | 0.76 | TSHR (0.39) | KCNN4TSHRALDH1A1MAPK1TAAR1 | |
| SCHEMBL15655727 | 0.76 | KCNN4 (0.31) | KCNN4TSHRALDH1A1 | |
| Bromide SCHEMBL102597 | 0.75 | KCNN4 (0.45) | KCNN4TSHRALDH1A1MAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507269-B1 | STABLE HYDROFORMYLATION CATALYST FOR PREPARATION OF HIGH N/ISO RATIO ALDEHYDE PRODUCT | EASTMAN CHEM CO (US) | 2020-09-23 | — | — | EP | disclosed |
| US-10766833-B2 | Hydroformylation method and catalyst using rhodium-ruthenium dual metal and tetradentate phosphine ligand | Wuhan Catalys Technology CO., LTD (CN) | 2020-09-08 | — | — | US | disclosed |
| EP-3507269-A1 | STABLE HYDROFORMYLATION CATALYST FOR PREPARATION OF HIGH N/ISO RATIO ALDEHYDE PRODUCT | Eastman Chemical Company (US) | 2019-07-10 | — | — | EP | disclosed |
| WO-2018044827-A1 | STABLE HYDROFORMYLATION CATALYST FOR PREPARATION OF HIGH N/ISO RATIO ALDEHYDE PRODUCT | EASTMAN CHEMICAL COMPANY (US) | 2018-03-08 | — | — | WO | disclosed |
| US-9687837-B1 | Stable hydroformylation catalyst for preparation of high N/Iso ratio aldehyde product | EASTMAN CHEMICAL COMPANY (US) | 2017-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10766833-B2 | Hydroformylation method and catalyst using rhodium-ruthenium dual metal and tetradentate phosphine ligand | HRH4, PPIP5K2, NUDT1 | KCNN4 2852/4885TSHR 3640/4885ALDH1A1 1224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.