Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMPR1A | P36894 | 1/20 | 0.37 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | PARG | Q86W56 | 3/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16464597 | 0.83 | BMPR1A (0.38) | BMPR1AACVRL1ACVR1CYP11B2 | |
| SCHEMBL19003060 | 0.81 | LPL (0.31) | — | |
| SCHEMBL14719343 | 0.77 | LPL (0.38) | BMPR1AACVRL1ACVR1CYP11B2 | |
| SCHEMBL19002979 | 0.76 | BMPR1B (0.32) | BMPR1AACVRL1ACVR1 | |
| SCHEMBL16464267 | 0.70 | LPL (0.36) | — | |
| SCHEMBL19521369 | 0.67 | FFAR1 (0.39) | BMPR1AACVRL1ACVR1CYP11B2MAP4K1 | |
| SCHEMBL24583674 | 0.66 | MAPT (0.49) | BMPR1AACVRL1ACVR1CYP11B2MAP4K1 | |
| SCHEMBL16465276 | 0.66 | BMPR1A (0.41) | BMPR1AACVRL1ACVR1 | |
| SCHEMBL23638476 | 0.65 | CNR1 (0.37) | PARG | |
| SCHEMBL22308284 | 0.65 | CYP2A6 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906539-B1 | INHIBITORS OF VIRAL REPLICATION, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES | HIVIH (FR) | 2017-06-21 | — | — | EP | disclosed |