Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMPR1B | O00238 | 1/20 | 0.32 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.32 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16465375 | 0.80 | LPL (0.39) | BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL19002971 | 0.76 | BMPR1A (0.37) | BMPR1AACVRL1ACVR1 | |
| SCHEMBL19003060 | 0.76 | LPL (0.31) | — | |
| SCHEMBL22655333 | 0.75 | LPL (0.37) | BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL505933 | 0.75 | LPL (0.37) | BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL14730026 | 0.73 | LPL (0.36) | — | |
| SCHEMBL21722599 | 0.69 | LPL (0.37) | — | |
| SCHEMBL29066212 | 0.68 | BMPR1B (0.32) | BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL505907 | 0.68 | MAP4K1 (0.35) | — | |
| SCHEMBL20217141 | 0.68 | AR (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906539-B1 | INHIBITORS OF VIRAL REPLICATION, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES | HIVIH (FR) | 2017-06-21 | — | — | EP | disclosed |