Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.62 |
| ▸ | MMP2 | P08253 | 4/20 | 0.62 |
| ▸ | MMP9 | P14780 | 4/20 | 0.62 |
| ▸ | EGFR | P00533 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003236 | 0.85 | MMP1 (0.62) | MMP1MMP2MMP9EGFRLMNA | |
| SCHEMBL19003345 | 0.83 | MEN1 (0.47) | MMP1MMP2MMP9EGFRLMNA | |
| SCHEMBL19003305 | 0.83 | MMP1 (0.63) | MMP1MMP2MMP9EGFRLMNA | |
| SCHEMBL19003261 | 0.81 | MMP1 (0.59) | MMP1MMP2MMP9EGFRLMNA | |
| SCHEMBL19003256 | 0.80 | ALDH1A1 (0.64) | LMNASMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL19003274 | 0.77 | MMP1 (0.58) | MMP1MMP2MMP9EGFRLMNA | |
| SCHEMBL19003277 | 0.75 | KMT2A (0.58) | EGFRLMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10940731 | 0.74 | SMN1; SMN2 (1.00) | MMP1MMP2MMP9EGFRLMNA | |
| SCHEMBL30764077 | 0.74 | SMN1; SMN2 (1.00) | MMP1MMP2MMP9EGFRLMNA | |
| SCHEMBL68058 | 0.73 | CA12 (0.46) | SMN1; SMN2ALDH1A1MAPTHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |