Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.59 |
| ▸ | MMP2 | P08253 | 4/20 | 0.59 |
| ▸ | MMP9 | P14780 | 4/20 | 0.59 |
| ▸ | EGFR | P00533 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003262 | 0.82 | EGFR (0.44) | MMP1MMP2MMP9EGFRMEN1 | |
| SCHEMBL19003354 | 0.81 | MMP1 (0.62) | MMP1MMP2MMP9EGFRMEN1 | |
| SCHEMBL19003255 | 0.81 | EGFR (0.47) | MMP1MMP2MMP9EGFRMEN1 | |
| SCHEMBL27752039 | 0.78 | RAB9A (0.71) | MMP1MMP2MMP9EGFRMEN1 | |
| SCHEMBL19003464 | 0.77 | EGFR (0.53) | EGFRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL19003251 | 0.76 | EGFR (0.68) | MMP1MMP2MMP9EGFRMEN1 | |
| SCHEMBL19003363 | 0.75 | RAB9A (0.52) | EGFRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL19003356 | 0.75 | TRPV1 (0.49) | EGFRMEN1KMT2ANPC1RAB9A | |
| N-(2-Chlorophenyl)Cinnamamide SCHEMBL3063601 | 0.75 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMEN1 | |
| N-(2-Chlorophenyl)Cinnamamide SCHEMBL2683663 | 0.75 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |