Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003354 | 0.83 | MMP1 (0.62) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL19003256 | 0.78 | ALDH1A1 (0.64) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL19003347 | 0.77 | CYP1A2 (0.54) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL9096395 | 0.76 | MAPT (0.74) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL9096393 | 0.76 | MAPT (0.74) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL19003274 | 0.75 | MMP1 (0.58) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL19003351 | 0.72 | LMNA (0.50) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL68058 | 0.72 | CA12 (0.46) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL68057 | 0.72 | CA12 (0.46) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL19003261 | 0.71 | MMP1 (0.59) | MEN1KMT2AMAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |